Results

Overview


The fashion and cosmetics industries are highly consumer-centric, impacting nearly everyone worldwide. These industries consume vast quantities of raw materials and can significantly harm the environment. In the face of escalating plastic pollution and the pressing need for environmental conservation, our project, PETAL , presents a novel solution by seamlessly integrating plastic waste management with the preservation of Indigenous sandalwood trees through the power of synthetic biology. Here, we will employ engineered microorganism to uptake plastic (PET) monomers and then utilize them to produce sandalwood oil.

Plant terpenoids and applications


Sandalwood depletion and its causes


  1. Tetali, S.D. Terpenes and isoprenoids: a wealth of compounds for global use. Planta 249, 1–8 (2019). https://doi.org/10.1007/s00425-018-3056-x
  2. Butnariu, M. (2021). Plants as Source of Essential Oils and Perfumery Applications. In Bioprospecting of Plant Biodiversity for Industrial Molecules (eds S.K. Upadhyay and S.P. Singh). https://doi.org/10.1007/s00425-018-3056-x
  3. Umra Aqeel, Tariq Aftab, M.M.A. Khan, M. Naeem, Regulation of essential oil in aromatic plants under changing environment, Journal of Applied Research on Medicinal and Aromatic Plants, Volume 32, 2023, 100441, ISSN 2214-7861, https://doi.org/10.1016/j.jarmap.2022.100441
  4. Shailja Choudhary & Gitika Chaudhary. (2021). SANDALWOOD (SANTALUM ALBUM): ANCIENT TREE WITH SIGNIFICANT MEDICINAL BENEFITS. International Journal of Ayurveda and Pharma Research, 9(4), 90-99. https://doi.org/10.47070/ijapr.v9i4.1895
  5. Sandalwood Information System, Institute of Wood Science and Technology (IWST)
  6. Sadler, Joanna C, and Stephen Wallace. “Microbial synthesis of vanillin from waste poly(ethylene terephthalate).” Green chemistry: an international journal and green chemistry resource: GC vol. 23,13 4665-4672. 10 Jun. 2021, doi:10.1039/d1gc00931a
  7. India recycles only 30 per cent of 3.4 MT plastic waste generated annually: Report (The Economic Times, 2023) https://economictimes.indiatimes.com/news/india/india-recycles-only-30-per-cent-of-3-4-mt-plastic-waste-generated-annually-report/articleshow
  8. Brandenberg et al. Microbial Cell Factories (2022) 21:119 https://doi.org/10.1186/s12934-022-01849-7
  9. Bao, T., Qian, Y., Xin, Y. et al. Engineering microbial division of labor for plastic upcycling. Nat Commun 14, 5712 (2023). https://doi.org/10.1038/s41467-023-40777-x
  10. Hernandez-Arranz, Sofía et al. “Engineering Pseudomonas putida for isoprenoid production by manipulating endogenous and shunt pathways supplying precursors.” Microbial cell factories vol. 18,1 152. 9 Sep. 2019, doi:10.1186/s12934-019-1204-z
  11. Yan Wang, Shenting Zhou, Qian Liu, Seong-Hee Jeong, Liyan Zhu, Xiangming Yu, Xiaojian Zheng, Gongyuan Wei, Seon-Won Kim, and Chonglong Wang Journal of Agricultural and Food Chemistry 2021 69 (44), 13135-13142 DOI: 10.1021/acs.jafc.1c05486
  12. Diaz-Chavez ML, Moniodis J, Madilao LL, Jancsik S, Keeling CI, et al. (2013) Biosynthesis of Sandalwood Oil: Santalum album CYP76F Cytochromes P450 Produce Santalols and Bergamotol. PLOS ONE 8(9): e75053. https://doi.org/10.1371/journal.pone.0075053
  13. Celedon, J.M., Chiang, A., Yuen, M.M.S., Diaz-Chavez, M.L., Madilao, L.L., Finnegan, P.M., Barbour, E.L. and Bohlmann, J. (2016), Heartwood-specific transcriptome and metabolite signatures of tropical sandalwood (Santalum album) reveal the final step of (Z)-santalol fragrance biosynthesis. Plant J, 86: 289-299. https://doi.org/10.1111/tpj.13162

Other References


  1. https://quintis.com.au/q-lab-knowledge-centre/sandalwood/indian-sandalwood
  2. https://www.volza.com/p/sandalwood/export/export-from-india/
  3. https://www.newindianexpress.com/states/karnataka/2023/Dec/17/felling-smuggling-of-sandalwood-trees-force-maker-of-mysore-sandal-soapto-import-oil-from-australia.
  4. https://www.researchgate.net/publication
  5. https://faolex.fao.org/docs/pdf/ton158188.pdf
  6. https://www.urban-farmers.co/government-approvals-required-for-chandan.html