Education

Introduction

The potential of synthetic biology will only be realized when society understands and accepts it more broadly. The main goal of AFCM-Egypt was to focus on the educational aspect of the project and elevate it to new levels. Education was prioritized as a key pillar for the success of the project and ensuring its long-term impact. The team realized that as we delve into the scientific part of our project, the impact of our idea and research does not exceed our ability to communicate it. This realization has shaped our educational strategy for this year. Initially, we created an online questionnaire with the help of public health doctors in our college. The purpose of the questionnaire was to assess general knowledge about synthetic biology, burn prevention, and first aid.

After analyzing the results, we found that a large percentage of participants from different societal groups have little knowledge of synthetic biology. Additionally, most people are not aware of how to deal with burns and have misconceptions about what to do. The positive side is that they have a desire to learn more about synthetic biology and how to prevent burns and provide initial treatment. Based on the survey results, we have developed a plan” BioBurn Initiatives “ for this year with a timeline from January to October.

The primary educational objectives of the plan were twofold, having ascertained that there were knowledge gaps reinforcing the urgent need for targeted education. The first goal is to demystify the field of synthetic biology, demonstrate its potential in addressing problems, and ensure the promotion of a deeper understanding and appreciation of it. The second goal is to significantly improve awareness about first aid for burns and their prevention. The educational plan is carefully designed and implemented, addressing misconceptions about GMOs, explaining complex concepts in accessible language, and connecting artificial biology to real-world applications.
The plan was developed to target five main categories: children, students, the general public, groups most vulnerable to burns, and healthcare workers. We organized various activities for each group, including visits to nurseries, workshops, and designing songs and short storyboards for children. For students, we organized visits to universities and workshops. We also targeted vulnerable job categories such as bakery workers and welders, and conducted visits to hospitals targeting healthcare workers.

To achieve these goals, we formulated a multifaceted approach that goes beyond traditional teaching methods. Our focus was on fostering inspiration and critical thinking, and ensuring that the educational materials are designed in an interesting and age-appropriate way. We involved specialists and professors to review the scientific content, and our media team designed educational content in an attractive way. We documented events to ensure accessibility and provide a solid foundation for future teams to build on and enhance the long-term impact of their work. In order to ensure inclusive communication, we fostered two-way dialogues by teaching and learning from the communities with which we interact. All our educational efforts were made available to everyone, and the outreach activities were aimed at promoting mutual learning through the effective exchange of knowledge and perspectives. Considering the differences in language and cultures in different regions, we prepared educational materials according to the culture and language of each region to facilitate comprehension and ensure wider reach. Additionally, we utilized social media platforms to reach a broader audience, and documented the team's journey and shared ideas to expand our educational scope beyond physical limits. Our vision and plan align with iGEM's vision, as we aim to build bridges between synthetic biology and society, rather than just disseminating information.

kids

SynBio Detectives

Description In a vibrant nursery, AFCM-EGYPT implemented the Synbio Detectives workshop. The team was keen to transform their young minds into heroes in the field of fire safety. Through interactive storytelling, engaging activities and hands-on demonstrations, children learned fire hazards and emergency prevention and response techniques.

This time, we ventured into the vibrant world of the nursery, where a unique transformation took place. Over a captivating journey filled with curiosity towards young minds, the AFCM-EGYPT team organized an immersive "Synbio Detectives" workshop. The team realized that creating an enjoyable experience that sparks curiosity and leaves a positive impression on young minds is key. Today, we decided to shift our focus to a critical aspect of everyday life: fire safety. Studies have shown that most burn accidents happen to young children. This realization prompted us to understand our role in raising their awareness about the daily risks they may face and how to prevent and handle them. The young detectives were eager to start a new adventure, learning about fire prevention, staying safe in emergency situations, and behaving responsibly. In the morning, the team shared the story "Maya and the Kitchen Dragon" with the children. As the story was told, the kids imagined themselves in Maya's shoes when she burned herself on a hot pot. They learned how Maya's mother handled the situation wisely, teaching her daughter about the sources of danger and how to deal with them. The story highlighted the importance of fire safety and the consequences of being reckless. After the story, the kids were asked questions to ensure they understood its meaning, and there was lively competition to answer them. The next task for the young investigators was very interesting. They were divided into teams and given checklists with pictures of potential fire hazards. The mission was to search for potential fire sources throughout the nursery, such as overloaded electrical outlets, flammable materials, and blocked escape routes. Then, they were to report these sources to adults without approaching them. The fastest team to complete the task correctly was the winner and received a reward. This interactive activity reinforced the importance of commitment and proactiveness in fire prevention. Afterwards, we conducted a fire safety demonstration where we showcased basic fire safety equipment and explained how to use it effectively. The children learned how to operate the equipment, the different types of alarms and safety symbols, and the importance of evacuation plans. To reinforce the concept, the children participated in a scenario simulating various fire emergencies. They were trained to contact the fire department, evacuate safely, and assist others in need. This hands-on experience helps develop critical thinking skills and the confidence to act calmly and effectively in real-life situations. To make fire safety concepts more relatable to young children, the team used fun analogies. Fire was described as a "hot dragon" that should not be touched. Hot liquids were likened to "sneaky ninjas" who could surprise and burn even if they did not appear to be steaming. The team made fire safety practice more enjoyable by turning the "stop, drop, and roll" technique into a fun dance move. When the music plays and the children shout "Fire!" they stop moving. When the music changes, they pretend to sleep on the floor, and when it changes again, they roll. Team members encouraged the children to practice these steps to reinforce the importance of this life-saving technique. The primary objective was to raise awareness among children about preventing the dangers of burns and how to act when they are exposed to burns. Children participated in a fun and interactive "Hot vs. Not Hot" sorting game, during which they categorized everyday items as either "Hot" or "Not Hot" based on their temperature and potential to cause burns. Children were given coloring sheets with pictures of kitchens and bathrooms. They identified hot objects (stove, iron) and safe objects (refrigerator, sink) by coloring them red and blue, respectively. When children made safe choices, the team praised them among their friends and described them as "heroes" to encourage them to continue making safe decisions. Conversely, if a child accidentally touched something hot, the team avoided reprimanding, explained the importance of being careful, and stressed the consequences of touching hot objects. When it comes to burn care, children were taught how to respond if they or someone else gets burned. They were encouraged to seek help from an adult and shown how to cool a burn under running water. To make the learning experience more realistic, we engaged the children in a role-playing activity. They took on the roles of patients, doctors, and nurses. The "patients" acted as if they had a small burn, and the "doctors/nurses" demonstrated the correct techniques for cooling and bandaging the burn. The day ended with the safety song "Be Safe from Fire," during which the children sang a catchy tune about fire safety and the importance of not touching hot things. The song was a fun and memorable way to reinforce key messages about fire safety.

Science Sparks "SynBio & Burn Care Discovery Day!"

Description: AFCM - EGYPT aimed to engage young students in an educational adventure in a primary school setting. The program offered the chance for students to explore the realms of cells, DNA, and fire safety. The team aimed for the students to take on the role of junior investigators of their own bodies, learning about DNA. They achieved this through interactive storytelling, hands-on activities, and engaging discussions, providing students with essential knowledge about fire prevention and first aid.

The AFCM–Egypt team organized a visit with the primary school students, as it is the first stage in their educational journey. At the beginning of the day, the team worked on simplifying some science concepts for the children. The adventure began with a captivating story that aimed to transport the young investigators to the city of the human body. The story dealt with interesting information about 'little detectives' who live inside our bodies and are known as cells. We tried to convey the concept of the cell to the children; our bodies contain many of them, and each group is responsible for performing a specific function in the body to help our lives continue. Curiosity filled the eyes of the children, as they were eager to learn more about the investigators inside their bodies. The children learned about the different types of cells, such as defensive cells and manufacturing cells, and how they work together to keep us healthy. Who among you wants to know what these little detectives are made of?" After this question, the children responded enthusiastically in unison, “We, we.” Our colleague Hossam Bannis explained that these investigators are very professional and always hidden, making them invisible to our naked eyes. However, we have invented a device called a "microscope" through which we can spy on them without being noticed. We told them that we were able to capture some detailed pictures of them, after which the children shouted in a victorious spirit, “We did it!” Through these pictures, we were able to identify the different organelles and specialized structures responsible for the complex functions of the cell, from the powerful mitochondria, which serve as the powerhouse of the cell, to the ribosomes, whose mission is to manufacture proteins. We used different colored beads and string to build models of DNA with the young investigators. This DNA is passed down through generations, from grandparents to parents and then to them. They learned how the sequence of these small molecules determines our unique characteristics and shapes, making each individual a masterpiece of nature's design. During the second session, our focus was on increasing awareness about burns and first aid in different scenarios, such as placing the burned area under running water. We also taught them about the preventive measures for burns and how to identify potential fire hazards. We used drawings, interactive images, and engaging lectures tailored to their age group to effectively convey the information. We addressed misconceptions that they had and encouraged discussions to enhance their critical thinking. The day was well-organized, and everyone had the opportunity to ask questions. We also had a Q&A session with a reward for the student with the correct answer. At the end of the day, we asked for feedback from the students and encouraged them to share what they learned with their friends and family. The students were excited and motivated to spread awareness. Overall, the day ended with great joy and anticipation for the next day.

Maya and the kitchen dragon story

The educational storytelling method is a modern and engaging approach that helps capture attention. Everyone enjoys listening to interesting stories with great interest, finding the narration enjoyable and exciting. Stories are an effective way to convey educational messages in a simple and easily understandable manner, providing a better opportunity for comprehension. AFCM-EGYPT created an amazing story titled "Maya and the Kitchen Dragon," suitable for children under 10 years old. The primary goal of the story is to teach children about burn prevention and appropriate first aid in case of burns. The story also delivers important instructions in an engaging manner that children must follow to protect themselves from the risk of burns. The story was transformed into a tool for creating meaning to engage learners, share knowledge, and broaden children's imaginations to envision the events more vividly. During the design of the story, the storytelling strategy took into consideration the following: - The story was natural and free from affectation. - The vocabulary and structure of the story were suitable for the students' language. - Both the content and meaning were appropriate for the students' mental level. - The story was of medium length, and high-level writing skills were utilized to ensure it was free of spelling errors. Multiple revisions were made before printing the story in more than one copy. The story was used during visits to nurseries, where it was shared with the children. Afterward, feedback was collected. When asked what they learned, the children's answers were very encouraging. Copies were distributed to several nurseries in different governorates and uploaded on social media platforms for free use. The aim was to create a foundation for further development and reach a larger audience

Be safe from fire song

We are dedicated to developing innovative educational techniques suitable for various age groups, aiming to leave a lasting impact. During our recent visit to the Faculty of Applied Arts, we gained insight into the significance of music in early childhood education. Music plays a vital role in stimulating learning and development, starting from the fetal stage. It has the ability to enhance a child's auditory senses, influence fetal heart rate, and trigger the release of endorphins in the mother. Furthermore, music promotes a child's capacity to concentrate and express themselves in more intricate ways. For children, music not only aids in memory retention and concentration but also enhances their cognitive abilities by engaging multiple senses and stimulating various areas of the brain. With this in mind, the afcm-egypt team has created an engaging song titled "Be Safe from Fire" to educate children about fire prevention and safety measures to avoid burns. The song features meaningful and expressive lyrics that are easy to learn and remember. It has been professionally designed to serve as educational content for use in settings such as nurseries. Singing and repetition of the song make learning smoother and more enjoyable for children. The soothing melody helps to calm and relax the children, facilitating better absorption of the information. To expand the reach of this educational content, we have uploaded the song on the team's social media platforms, including Facebook, Twitter, Instagram, and YouTube. Additionally, we have distributed copies of the song to several nurseries in different locations and requested feedback on its impact. The response has been overwhelmingly positive, with children embracing the song wholeheartedly.

Students

DIY workshop

Description: The AFCM-EGYPT team organized a workshop for undergraduate students to train them in basic wound dressing skills. The workshop included interactive lectures, engaging discussions, and hands-on practice. It emphasized the importance of antiseptic techniques and appropriate procedures for wound care. Additionally, the workshop addressed the potential of synthetic biology in wound healing.

The AFCM-EGYPT team organized a workshop for undergraduate students from different colleges. The purpose of this workshop was to train participants in an essential skill, the "wound dressing technique." After the team announced the workshop, many students registered for it due to their keen interest in learning this skill. Since injuries are a common occurrence, mastering this technique is crucial for everyone. The morning session started with an engaging lecture that delved into the intricate world of wound healing. Team members introduced themselves to the attendees and eagerly interacted with them. We discussed various aspects of wounds such as their occurrence and the intricate biological processes that govern the body's incredible ability to heal itself. In addition, every stage of the healing process - from the initial inflammatory response to the delicate tissue regeneration process was discussed. The team then discussed this year's therapeutic approach to improve the wound healing process and reduce scarring with attendees. We talked about simple concepts of synthetic biology and its significant role in solving various problems across different fields, using live examples. The discussion also covered burns, their causes, classifications, how to avoid the risks, and the necessary first aid. Following this, there was an engaging panel discussion among all attendees, where we exchanged views on the latest developments and future trends in this field. In the afternoon, we started a new practical adventure in dressing wounds with plastic surgeon Dr. Esraa shalan. We prepared various tools for the process, such as alcohol pads, bandages, and gauze swabs. The doctor presented each type of tool separately, explaining their different uses and their roles in the dressing process. He emphasized the importance of using the antiseptic technique at every step to prevent the accumulation of bacteria and the occurrence of complications such as abscesses. The students were split into small groups and given tools and simulation models to apply what they learned in practice. The lecturer supervised the activity, providing guidance and feedback to ensure the skill was mastered effectively. During the day, students collaborated, experimented, and shared their ideas, turning their new knowledge into tangible creations. The team emphasized the importance of sharing what they learned with friends and family to raise awareness on a broader scale. Ultimately, the team members were eager to gather feedback from the participants about the day's activities. The responses were very positive and served as motivation to plan further activities on the path to achieving our goal.

iGEM talk

Description: This time AFCM-EGYPT targeted high school students, to introduce them to the exciting world of synthetic biology. The activities were interactive, the presentations were engaging and suitable for their minds. The team opened the way for discussion with the students to open their minds. Our Goal was to ignite the student’s curiosity and develop their passion for scientific exploration. The team showcased the potential of synthetic biology in various fields and encouraged the students to become involved in it in the future.

Our primary goal is to introduce future generations to the field of synthetic biology. We aim to open their minds to the fascinating aspects and potential of this field. The AFCM iGEM team has created an accurate, simplified, and accessible piece of literature to illustrate the basic components of genetics and synthetic biology. This time, we focused on high school students as it is the stage before university education. Our goal is to solidify some concepts about synthetic biology with them. We want them to be familiar with it during their university stage so that they can participate in this field and develop their interest. At the start of the day, the team leader introduced the team members to the audience. He shared with them our activities, previous projects in the diagnostic and therapeutic field, and our achievements over the past years. The events began with an engaging introduction that skillfully bridged the gap between the familiar and the unknown. By using relevant examples and real-world applications, our team successfully piqued the students' curiosity and established a strong foundation for further discussions. We presented an easy-to-understand explanation of synthetic biology, covering the basics of DNA, plasmids, restriction enzymes, and synthetic biology. In the first session, the team shared how to reprogram organisms through synthetic biology. They provided examples to illustrate the profound impact synthetic biology can have on improving human health. They discussed the role of synthetic biology in rewriting the genetic codes of cells and creating new biological systems, which piqued the students' curiosity and demonstrated the significant power of synthetic biology. The team also shared its applications in bacteriological engineering, tissue regeneration, and the production of drugs to treat previously incurable diseases. Additionally, they highlighted its role in diagnostics and the development of innovative diagnostic systems for early disease detection. During the second session, the team aimed to deepen the students' understanding of the basic principles of synthetic biology. To achieve this, we involved the students in a series of interactive activities to ignite their passion for scientific experimentation. The activities included the design of artificial organisms using computer simulations and the use of the hdock server to visualize three-dimensional RNA, DNA, and docking protein integration using a hybrid strategy. Additionally, we facilitated lively discussions about the potential benefits of synthetic biology and its ethical and societal implications. Our goal was to encourage the students to think critically and innovate responsibly. These discussions covered topics such as environmental sustainability and intellectual property rights. In the end, the final session was an open dialogue for students. They discussed their ideas on how to become active participants in shaping the future of artificial biology and explored career opportunities in the field. An interesting topic of discussion was the importance of and how to collaborate between different disciplines. They also discussed ideas for innovative solutions to address global challenges using the principles of artificial biology. Afterward, we distributed a feedback questionnaire to the participants. The purpose was to assess the strengths and weaknesses of the literature from their perspective and to explore whether their needs were fully met. We also received recommendations to improve the quality of literature for future initiatives. Additionally, we were eager to provide the attendees with the educational materials used as a reference and also provided them with means to communicate with the team for inquiries.

Bio Art blast

Description: AFCM-EGYPT aimed to bridge the worlds of science and creativity by collaborating with the Faculty of Arts. The day was filled with various events, including interactive lectures, discussions, a vibrant art workshop, and the announcement of an art competition. The team and students exchanged energetic ideas and explored the intersection of synthetic biology, wound healing, and art. They also discussed the potential of art therapy in promoting healing and generating new ideas for educational materials.

Who doesn't like drawing? When you express what is inside you using art, it is truly wonderful. So what's wrong with linking synthetic biology with art? This question was answered by arranging a visit to the College of Arts with officials there. The AFCM-EGYPT team visited the lively campus of the Faculty of Arts, where the realms of art and science come together. The team received a warm welcome from the college representatives and some students. They were eager to learn about the team's work and understand what synthetic biology is. The day started with a tour of the college's roads and suburbs. The tour included explanations of the different college departments and their respective work. Throughout the tour, we came across beautiful works of art, including paintings, sculptures, and designs created by college students, showcasing the beauty of their artistic talent. It was a fantastic start to the day and set a positive tone for the rest of our activities. After that, there was an interactive lecture by the team members, where the team leader introduced the team to the attendees. He shared the team's contributions to the iGEM International Competition, its diagnostic and therapeutic projects, and its achievements in the past years, whether medals or nominations. This was followed by an overview of wounds, including their causes, the complex processes involved in wound healing, and the challenges presented by scar formation. Another team member discussed burns, their degrees, causes, first aid protocol, prevention, and their physical and psychological impact. We also presented this year's project and our vision for a future where synthetic biology can innovate wound healing, reduce scar formation, and promote physical and emotional well-being. The audience, composed of a diverse mix of art students and university professors, listened attentively, reflecting a thirst for knowledge and a spark of curiosity in their eyes. After the lecture, a lively discussion session broke out, bringing together professors, students, and team members. The dialogue flowed effortlessly. There was a Q&A session during which the audience's questions were answered. We discussed the topic of art therapy, which involves communicating with the patient through drawing. This allows the patient to reflect their inner feelings in their drawings. By exploring and interpreting these drawings, the patient gains insight into themselves, which can lead to progress in treatment. We hosted a collaborative artistic workshop that brought together participants from medical and artistic backgrounds. We shared ideas and information to create artwork inspired by scientific concepts of wound healing. Students from both fields worked together on the artworks. Mixed teams were formed and challenged the participants to find creative ways to explain the science behind our projects to a non-expert audience. The workshop was a great success, with all teams showcasing their imagination and creativity. They generated excellent ideas for effectively communicating our goals. For instance, we proposed creating a graphic story for children to raise awareness about the dangers of burns and how to prevent them. The participants also discussed producing a catchy song for children with the same educational content. It is believed that using attractive audio and visual effects can leave a lasting impression, especially when designed to be engaging. We launched a competition for students to create the best artistic painting titled "The Impact of Burns on an Individual." A deadline was set to receive the designs. Following the submission of all entries, the team convened to select the winning painting. The designs were all impressive, making it challenging to choose a winner as every entry reflected considerable effort. The winning painting was recognized, and all participants were thanked for their contributions. We were pleased with the positive feedback from everyone we interacted with throughout the day, expressing gratitude for our efforts. We were especially gratified by the emphasis on the importance of art and its impactful role. They pledged to collaborate with us in developing artistic educational materials to help us effectively communicate and express our ideas to a broader audience. At the end of the day, we were keen on collecting feedback from participants throughout the event to ensure that it met their needs and expectations. This experience served as a strong reminder that the quest for knowledge goes beyond specific fields of study. It shows that diverse viewpoints from different disciplines can come together to foster innovation. As we reflect on today's events, we realize that our presentation wasn't just a scientific discussion, but rather a journey of learning and mutual dialogue. This event emphasized the connection between art and science and their potential to work together toward a shared objective of enhancing human health and well-being.

Benha university visit

Description: We invited a delegation of students from Benha University to visit our college to raise awareness about synthetic biology and burn care. During their visit, we engaged in various activities and had discussions on important topics related to synthetic biology and life skills. Additionally, we talked about first aid for burns and how to prevent them.

We invited a delegation from Benha University, one of the top universities in Egypt, to visit our college. The delegation consisted of students from various faculties and academic years. The visit started with a warm welcome, followed by a tour of the college to familiarize them with our campus. The first session began with an introductory lecture about the AFCM-Egypt team and its previous participation in the IGEM Genetic Engineering Competition since 2016. We also provided an overview of past project ideas and a simplified explanation of the current SONG-H therapeutic project, which focuses on improving wound healing and reducing scarring. Next, we conducted a lecture on the fundamentals of synthetic biology and related concepts. We covered topics such as DNA and protein synthesis, how cell function changes to perform different functions using synthetic biology, and important topics like bioengineering, synthetic genomics, protocell synthetic biology, unconventional molecular biology, and in silico techniques. Following the lecture, we held an open dialogue session with the students to address any questions or inquiries they had about the topic. The second lecture was on mathematical modeling, presented by our colleague Ahmed Wael. He simplified concepts about the topic and discussed its role in describing real-world problems using mathematical concepts and language. He also provided references and educational videos for further immersion in the topic. Afterward, our colleague Ahmed Shaalan delivered a lecture on digital marketing and its current role in marketing products through digital advancements. He also discussed entrepreneurship, how to develop a project plan for market success, and the strengths and weaknesses of products. In the afternoon, we talked to them about burns in general, including their causes, classifications, and first aid for different types of burns. We also discussed burn prevention and shared a guide which received great admiration from the students. Finally, we urged the students to spread the knowledge they gained throughout the day to their friends, colleagues, and parents to raise awareness. The day concluded with the students expressing their gratitude for our efforts and wishing us success in the future.

Tanta Royal school

Description: We visited one of the most famous schools in Gharbia Governorate. After several discussions, we were able to convince them that the students lacked knowledge of synthetic biology and burn care. As a result of our efforts, the school administration promised to provide expert help in adding elective courses on synthetic biology to the curriculum and developing lectures on burn care to raise awareness among the students.

Our goal has always been to establish a standardized curriculum in pre-university schools to educate students about the basics of scientific research and synthetic biology. We believe in the significance of this field and its potential to address many of the challenges humanity faces both now and in the future. Recently, the AFCM-Egypt team visited Tanat Royal School, one of the oldest schools in Tanta, offering primary, preparatory, and secondary education under the international IG education system. During our visit, we introduced ourselves as the AFCM-Egypt team and highlighted our past achievements and participation in the international IGEM competition. We provided the school administration with a brief overview of synthetic biology using simple language and real-life examples of how it can address various challenges. Additionally, we shared the results of a questionnaire, which revealed a significant lack of awareness about synthetic biology and its principles. We have emphasized that students are usually first introduced to the concept of synthetic biology at the university level. In some colleges, they are not exposed to it at all. We also presented our SONG-H therapeutic project for improving wound healing and reducing scarring this year. We discussed the importance of addressing the lack of knowledge in this crucial area with the school administration. Following our discussion, the school administration acknowledged the importance of our work and recognized the existing knowledge gap in both synthetic biology and first aid and burn prevention. The school has committed to studying the subject matter and intends to involve experts in synthetic biology to develop elective courses for students at various educational stages. Moreover, they have assured us that in their upcoming educational plan, they will collaborate with doctors, firefighters, and safety specialists to conduct sessions throughout the year, raising awareness about burn care among the students.

Educational course

Description: The AFCM-EGYPT team targets the accessibility and great coverage of online platforms to spread general knowledge about synthetic biology. By designing free online courses with supplementary resources, the team encourages the learning process and delivers complex scientific concepts in an easier simplified manner.

In today’s world, education is no longer confined to traditional classrooms. Online courses have been used as powerful learning tools, offering flexibility and accessibility. In consequence, the AFCM iGEM team created an online course to introduce the fascinating world of synthetic biology especially for the high school students. This online free course provides a comprehensive overview of synthetic biology and human genetics. Developed by the AFCM team using certified sources and the up-to-date data, the course content has been reviewed by AFCM College’s research department and specialists. The course begins with an introduction to human genetics, covering essential topics such as DNA, RNA, proteins, transcription, and translation. It then delves into synthetic biology, exploring genetic engineering, its tools, and scientific principles. The course also includes discussion on genetic circuit components and the importance of genes in reports. Additionally, various biosafety levels and practices to prevent unintentional or accidental release of biological agents and toxins are covered. Moreover, the course explains metabolic engineering, which involves modifying the internal metabolic pathway toward the targeted goal, using graphs and models. The principle of logic gates controlling genetic circuits is defined. Finally, real-life applications of synthetic biology in different fields, such as pluripotent stem cells and nanotechnology in pharmacological science, are demonstrated. We have also used this course in our various educational activities throughout the year. We posted it on our social media pages to reach a wider audience. To facilitate the learning process, the AFCM team depends on variable assistive equipment and tools like visual aid, short videos, animation and diagrams. Also, real-life examples are used throughout the course to fill the gap between the theoretical knowledge and its applications. For deeper learning and specialization, The AFCM iGEM team offered additional online websites and resources in addition to more specific courses with contacts of the team members. Ensuring the easy accessibility of further earning process and greater coverage of gaped knowledge. To reinforce learning, the course includes variable checkpoint quizzes to engage understanding and ensure that scientific content is effectively delivered. At the end of the course, students can provide feedback through an online platform, which helps the team refine and improve the course for future learners.

Public

Tree planting event

Description: On World Earth Day, AFCM-EGYPT organized a tree planting workshop. The team combined synthetic biology, environmental sustainability, and community engagement. Through an engaging presentation, interactive tree planting, and a hands-on DNA extraction workshop, the team inspired and educated individuals to actively contribute to a more sustainable future

This time, AFCM-EGYPT went on a unique journey to intertwine the principles of synthetic biology, environmental sustainability, and community engagement. On World Earth Day, the team organized a "tree planting event" to motivate and educate individuals to actively contribute to shaping a more sustainable future. The day kicked off with an introductory lecture about the team and its previous involvement in the IGEM International Synthetic Biology Competition. The team then provided a simple definition of synthetic biology and discussed some of its basic concepts. They emphasized the importance of synthetic biology in addressing global challenges and its role in various fields such as agriculture. This was followed by an open dialogue about the role of synthetic biology in current issues like climate change and improving environmental sustainability. After the presentation, the team and the audience headed to a garden to plant some plants and trees together. While planting seeds, the team discussed the importance of synthetic biology in agriculture, including increasing production, improving crop quality, and reducing agricultural pests. To wrap up the day, the team held a workshop with students, where they demonstrated how to extract DNA from a tomato fruit. They provided students with a manual containing the necessary steps for the process and guided them through the experiment, also showing them how to use a microscope to see DNA more clearly. Throughout the day, we carefully receive questions from attendees and try to answer them in a simplified way. Receive suggestions and feedback from attendees to improve future events. This simple and enjoyable activity provided hands-on experience with the basic principles of molecular biology. Participants carefully followed the instructions and were very happy when they successfully conducted the experiment. The team meticulously documented the event and successfully convinced the audience that their activities would help shape the future of synthetic biology. The team took care to implement the workshop carefully and committed to mutual learning. The team made exceptional efforts to include more people in shaping, contributing to, and participating in synthetic biology.

Meet an expert!

Description: The AFCM-EGYPT team has created a video tutorial on burn care to share knowledge and empower others. Our goal is to address the lack of information on this important health issue that impacts many people. The team has taken the initiative to make a positive impact on the community by using technology and collaborating with medical staff. We have hired a medical expert and utilized social media to achieve their goal.

We recognize that information moves rapidly in our digital world. To keep up with this change, the AFCM-EGYPT iGEM team has set out to leverage digital transformation to expand its educational mission on burn prevention. We created an engaging video tutorial featuring Dr. Ali Moussa, a specialist in Plastic Surgery. This video serves as an educational tool, as well as a platform for raising awareness and community involvement. The team commenced their journey by producing an educational video. They carefully planned the content to cover the most crucial aspects of burn care. Dr. Ali Moussa's expertise in cosmetology, with a focus on burn care, played a crucial role in this initiative. The doctor provided clear explanations and addressed many important topics. He began by discussing the definition of burns, their causes, and classifications. Subsequently, he covered first aid protocols for each type of burn and effective prevention strategies. Furthermore, he dispelled common misconceptions about treating burns, such as the use of oils and toothpaste. The team recognized the importance of using social media as an educational tool. They professionally utilized their pages on various platforms such as Facebook, Instagram, and YouTube to share the video widely and reach a diverse audience. To create anticipation and encourage followers, the team publicized the video through attractive posts and trailers before its release. After releasing the video, the team aimed to facilitate dialogue and address public concerns. They offered a way for viewers to connect with Dr. Ali by allowing them to submit their questions directly and receive expert insights and personalized guidance from the specialist, empowering individuals to take an active role in their health and well-being. The team's goal with the video was not just instant viewership, but to create a valuable resource that is easily accessible indefinitely. The educational video serves as evidence of the team's commitment to empowering individuals with fundamental knowledge about burn care.

Guidebook

Burn injuries can be prevented with a few proactive steps. The AFCM iGEM team's main goal is to raise awareness and address public health concerns related to burn injuries. AFCM EGYPT has implemented a systematic problem-solving strategy to tackle the epidemiology and data related to burns. Our research started with an exploration of the epidemiology of burn injuries, including their characteristics, types, grades, and causes. As we progressed, the team delved into existing solutions to the problem, focusing on medical treatments, grafts, and rehabilitation options available for burn victims. Additionally, we explored alternative solutions that could offer new perspectives. The team analyzed the collected data, interpreted the results, and compiled them into a manual guidebook written in simple, understandable language. This guidebook provides a comprehensive view of burns, discussing their causes, types, and grades. Furthermore, it includes detailed discussions in simple language about current treatments, along with guidelines on first aid, management techniques, and prevention. This guidebook aims to help burn patients and their families recognize the condition and manage the physical and psychological treatment journey. The AFCM iGEM team prioritized the distribution of the guidebook to the local community during visits, as well as providing a digital copy on the team's page across all platforms.

Animal shelter visit

Description: After a tragic fire in an animal shelter, we tried to turn it into an opportunity for healing, resilience and education. The AFCM-Egypt team responded to the incident with compassion and action. We engaged with the community, assessed needs, and began our awareness campaign. Our first goal was to spread awareness about burn care in collaboration with Ahl-Masr Foundation. We have strengthened fire safety education and provided first aid training. We used educational materials in their common language and appropriate to their culture. With them, we explored the potential of synthetic biology to treat burns.

Day 1:
One day, while we were busy preparing for the project, breaking news on television caught our attention. There was a large fire at an animal shelter in a village in Egypt, resulting in many injuries to both animals and people. We were deeply saddened and decided to go there to learn more details about the incident and share the pain and sorrows of the people there, as well as try to help them. When we arrived, the atmosphere was filled with emotions – sadness over the recent fire that destroyed the animal shelter, and hope for healing and rebuilding. The team tried to immerse themselves in the community's pain and resilience. We visited the animal shelter, which was charred, a stark reminder of the tragedy. The team members tried to talk to the villagers, share their pain, try to support them, and find out the details from them to try to put our hands on the problem. The cause of the fire was one of the children taking an ember from a burning fire in the street to get rid of the dirt and threw it near the shelter. It was only a few seconds before it burned. The workers in the shelter did not know what to do at the time or how to react. All they were thinking was how to save their only source of livelihood. Someone said, "Death was very close to me today!" We communicated with firefighters and learned that the challenge was difficult as most of the buildings in the village are connected and contain many easily flammable materials. They commented on the awareness of individuals and how they deal with emergencies. The villagers initially tried to control the fire themselves using simple traditional methods, and calling the fire brigade was their last resort! They also did not have a good evacuation plan that would protect them and their animals. On the contrary, the procedures they followed made matters worse. Through the dialogue with the healthcare providers, we knew the challenges they face during emergencies and discussed ways to improve communication between them and healthcare facilities. The villagers deal with various injuries in a way that makes the condition worse. They used ingredients such as toothpaste and ice to treat the burns that made the burn worse. Therefore, it is necessary to increase awareness among villagers about first aid and preventive measures for burns. The visit to the shelter was a powerful reminder of the human-animal relationship and the importance of community. The AFCM-EGYPT team left the village after getting our hands on the important points. We conducted a needs assessment within the affected village to understand the extent of the fire's impact on the community and identify specific needs related to animal welfare and community support. Starting with trying to find solutions to compensate them for the burning shelter and making sure to increase their awareness of how to deal with these matters better.
Day 2:
We made a second visit to the affected village to turn a tragic fire incident into an opportunity to support the affected community. AFCM-EGYPT collaborated with various organizations and groups to gather insights and ideas for shelter rebuilding, while addressing community concerns and providing support for recovery efforts. We collaborated with Ahl-Masr organization to provide emotional support, practical assistance, and educational resources to community members. Our approach was respectful of their local customs and beliefs. In addition, we focused on raising awareness within the community about fire safety, disaster preparedness, and animal welfare. We also provided educational materials and workshops to improve awareness and knowledge about fire prevention, safety measures, and the responsible disposal of waste. To ensure accessibility, we translated educational materials into local languages and provided them in accessible formats, including expressive drawings without words for the benefit of the uneducated population. Throughout the day, we interacted with the villagers, sharing our activities and objectives, posting educational materials in the village, and engaging in talks to improve awareness and knowledge within the community. We also led a workshop to train animal shelter employees on important techniques for fire prevention, first aid, and animal rescue. Additionally, we discussed the concept of synthetic biology in a simplified manner and its potential role in solving various problems, including treating burns and reducing resulting scars. Overall, our efforts were well-received by the community, and they appreciated our support and initiatives. Dr. Ayman Shawky, our team's PI, advocated for the implementation of a fire safety plan for the affected village and adjacent areas. We highlighted the necessity of organizing public talks and workshops to educate the community about fire safety procedures, burn prevention, first aid, and evacuation plans. Also,This accident motivated us to develop educational programs for children and adolescents in local schools, focusing on fire safety and prevention measures to underscore the importance of burn care from a young age.

Educational video

We recognized the significance of social media as a powerful tool for our educational plan this year. AFCM-EGYPT decided to make the most of it by reaching out to a social media content creator named Tarek Mohamed. After introducing ourselves as the AFCM-EGYPT team, we briefed him on our project, SONG-H, which aims to enhance wound healing and minimize scarring, particularly from burns. Tarek was enthusiastic about the idea and offered to help raise awareness about it. We provided him with accurate medical information about burns, their causes, classifications, and first aid procedures. We also emphasized preventive measures to reduce the risk of burns. Tarek adapted the script to make it suitable for audiences of all ages and cultures, and added engaging visuals to aid understanding. The video, presented in an interesting format, was well-received and widely shared on social media. To reach a broader audience, we included subtitles in multiple languages. Additionally, we shared the video on our official social media pages, such as Facebook, Instagram, TikTok, and YouTube. Furthermore, we uploaded the video to Video Igem Universe for use as an educational resource on the IGEM website, benefiting both current and future IGEM teams.

Healthcare workers

Helmeya Military Hospital visit

Description:
In a two-day trip, the AFCM-Egypt team embarked on Helmeyet Military Hospital.Our main goal was to promote burn prevention and education on first aid procedures, and to explore the potential of synthetic biology in wound healing and scar reduction.Through interactive workshops, ethical discussions and media materials, we interacted with patients, healthcare professionals and hospital leadership. The visit had many dimensions as the team fostered a sense of community, and addressed ethical concerns related to synthetic biology.

Day 1 :
At dawn one day, the AFCM-Egypt team arrived at Helmeya Military Hospital in the heart of Cairo. There, we were warmly welcomed by hospital staff, and a palpable sense of purpose and excitement filled the air. After introductions and a short tour of the facility, the day began with a lecture by the hospital’s burn specialist, Dr. Omar Hani. The lecture provided a general overview of burns, including their causes, degrees, and the correct first aid. Dr. Hani listened to our questions carefully and answered them with great accuracy. The team members took notes of the important information in preparation for its future dissemination on a wider scale to ensure greater benefit. During a thorough tour of the hospital facilities with the medical staff, we learned about their current methods of wound care, scar management, and emergency procedures. The tour allowed us to interact with patients and their families, hear their personal stories and experiences with burns. We also had an open discussion with hospital staff, and patients to share insights about wound healing and scar formation. A key part of the conversation focused on the challenges that patients and healthcare professionals face, as well as the potential of synthetic biology to address these challenges. AFCM-EGYPT organized an interactive workshop that focused on synthetic biology and its applications in healthcare, particularly in wound healing and scar reduction. The presentation was engaging, featuring clear explanations, live pictures, and interactive. Panelists expertly answered audience questions, sparking lively discussions about the potential of synthetic biology to offer unconventional solutions to health challenges like burn scar management. The hospital staff shared details about current treatment protocols and patient concerns, leading to a vibrant exchange of ideas. The team proposed a potential treatment using synthetic biology to reduce the formation of scars, generating a cascade of inquiries. A question and answer session allowed the team to address concerns from both hospital staff and patients. We distributed copies of the guidebook to patients, their families, doctors, and nurses, and asked for their feedback. After reading it, they expressed admiration for its design and the importance of the information. They suggested adding a section on first aid for major burns and creating fire prevention awareness signs for places where workers are at risk of burning. Their feedback opened new horizons for us to consider. Following this, the team presented their project objectives, detailed the day’s activities, and shared valuable insights gained from their community interactions with the hospital leadership. The hospital leaders admired the guidebook presented to them and found its content to be suitable for everyone. They even decided to print more copies to distribute them more widely. Before leaving, the team placed some copies of the guidebook in the hospital’s reception area for easier access by future visitors. Finally, as the day came to a close, the team gathered to review the day’s activities, exchange notes, and share their thoughts and feelings. It was evident that all team members recognized the impact they had on patients, their families, and hospital staff, which brought them a sense of fulfillment and achievement..
Day 2 :
After the successful first visit, the AFCM-Egypt team returned to Helmeya Military Hospital with a renewed purpose and new resources. This time, we brought scientific information posters and leaflets designed to educate patients and their families about burn prevention and necessary first aid procedures. We distributed these materials throughout the hospital to ensure easy access for patients, families, and employees. The impact was immediately evident as the vibrant images and clear instructions on the posters and flyers attracted attention, sparking curiosity and prompting many questions. Team members stationed themselves near the displays, ready to answer inquiries and observe people's reactions. A diverse group of healthcare professionals engaged in a lively and thought-provoking exchange of ideas, discussing the ethical considerations surrounding synthetic biology and its applications in burn care. They addressed topics such as informed consent, patient autonomy, safety, equity, and environmental impact. The team stressed the importance of focusing on patient autonomy and informed consent, as they discussed different strategies for achieving them. They also ensure that patients are fully informed about the nature of synthetic biology treatments, their potential risks and benefits, and their right to make informed decisions about their treatment options. Also, the potential risks associated with the use of engineered cells or biomaterials, such as unintended immune reactions and consequences were discussed. Therefore, participants stressed the importance of confirming the effectiveness of treatments and patient safety by conducting clinical and preclinical trials before making them available to patients. Regarding the high cost of treatments using synthetic biology, doctors emphasized that solutions must be considered to make them available and affordable to all patients in need, regardless of their socio-economic status or geographical location. Some suggestions included government funding and partnerships with non-profit organizations.The group discussion concluded with an open question-and-answer forum. The dialogue was interesting and informative, drawing on their knowledge of synthetic biology, bioethics, and healthcare policy. The session concluded with the team providing participants with a list of peer-reviewed articles and bioethics guidelines for further information to enable participants to continue learning and engaging with the ethical considerations surrounding synthetic biology. The team's progress was presented to the hospital leadership, emphasizing the impact of our activities on humanitarian practice. The presentation included an explanation of the ethical considerations discussed with healthcare workers, demonstrating the team's commitment to ethical research. The hospital leadership deeply appreciated the team's efforts, recognizing the value of our educational materials, their interaction with patients and healthcare workers, and their commitment to ethical considerations.

Ahl-Masr program

in progress …

High risk groups

Description:
After conducting a comprehensive study on burn injuries, the AFCM iGEM team was able to identify high-risk industries in Egypt. We visited bakeries, welding and brick factories to assess working conditions, identify safety needs and provide educational sessions on burn prevention, first aid and the importance of personal protective equipment. Our main goal was to focus on practical solutions to improve workplace safety and reduce burn injuries.

The AFCM iGEM team focused on studying burn injuries, their causes, and conditions, with the aim of identifying populations at high risk for burn injuries. Industries such as welding, bakeries, and brick factories were found to have a higher incidence of burns compared to other industries. The team conducted visits to various bakeries, welding, and brick factories to identify potential risks and assess work conditions to better understand the safety needs of the workers. Also we wanted to assess their knowledge of burn care and first aid when they are injured in general or burned in particular. One common issue identified was the absence of first aid points or aid boxes in welding factories for a rapid response to emergencies. There was a significant lack of awareness of burn prevention or first aid in case of injury. After analyzing the collected data, the team met with Eng. Amir Ismael, a specialist in fire safety regulations and manager of a fire safety equipment company. This meeting provided valuable insights into the ideal personal protective equipment for workers, fire extinguisher systems, and fire safety policies in factories. Following this, the AFCM iGEM team returned to the same places for a second visit. There we conducted specialized sessions tailored to each place's specific conditions. The first session focused on burn prevention and protective measures, while the second session discussed burn first aid and when to seek hospital support. The team emphasized the importance of ensuring ergonomic working conditions, supplying personal protective equipment, modifying machines and work environments, and providing rapid responses to different emergencies. The significance of applying fire detectors and extinguisher systems to protect workers' lives against physical hazards was also stressed.

Fig 1. gauze none bftth fg [7].

Fig 2.

References

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[2] lorem ibsum

Description Value Units Reference
K1 Rate of expression of external domain (CCP1) Syn-Notch receptor 0.001 day-1 × cell-1 [1]
K2 Reciprocal rate of degradation of MSCs 15 Days-1 [2]
K3 Rate of formation on Syn-Notch receptor on MSCs 0.033 Days-1 [1]
K4 Rate of the binding state between S and B 0.000411 day-1 × cell-1 [3]
K5 Reciprocal rate of degradation of autoreactive B-cell 30 Days [4]
K8 Rate of dissociation of the binding state 0.001 day-1 [-]

Introduction

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