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Background

On Sustainability & Alternative Biomaterials

In an ever-changing and logarithmically progressing world, technological advancement and continued aggressive industrialization often blur the line between good and bad. As we strive for progress, the environmental toll of conventional manufacturing and material use becomes increasingly apparent; it is more important now than ever to shift our focus towards sustainability and accelerate the application of alternative biomaterials.

Biomaterials, derived from renewable biological sources, offer a promising solution to many of the ecological challenges we face today. Unlike traditional materials that rely heavily on finite resources and energy-intensive processes, biomaterials are renewable, biodegradable, and less energy-hungry. Sustainability through biomaterials hinges on their ability to reduce environmental impact at every stage of their life cycle. From production to disposal, these materials have immense potential to minimize carbon footprints and reduce pollution.

A circular economy also arises from the use of biomaterials, emphasizing reuse, recycling, and regeneration. Biomaterials can be repurposed or recycled into new products, minimizing waste. More than that, biomaterials offer socioeconomic benefits as well. Locally sourced or synthetically generated renewable materials can boost regional economies and create jobs in agriculture, research, and manufacturing. This reduces reliance on global supply chains, enhancing resilience against political disruptions.

Despite obvious benefits, alternative biomaterials still face many challenges in scalability and application versatility. Our project aims to address these issues through establishing a platform for carbon-negative spider silk production that is sustainable, versatile, and scalable.

For more information on our project's sustainable development impact, visit sustainable .


Spider Silk - A Superior Biomaterial

Spider silk has been proven by extensive research to be a remarkable natural material known for its extraordinary properties; It has an unmatched mechanical strength that is 5x tougher than Kevlar and 3x more flexible than nylon, making it one of the most durable materials found in nature. More than that, spider silk's diversity (41,000 species of spiders produce silks. 7 types of silk are produced per spider, each with different properties.) makes it extremely versatile and suitable for a wide range of applications.


The Spider Silk Production & Application Bottleneck - Challenges yet to be solved.

There are two main challenges facing spider silk production and utilization right now:

  1. A lack of understanding of how its protein sequence correlates to mechanical properties, which leads to minimal customization for application.
  2. A lack of standardized protocol and workflow for its production, purification, and post-processing, leading to issues in scalability.

Our project, SAC, aims to address these two main challenges in order to accelerate spider silk's real-world usage as an alternative biomaterial.

Our Solution

SAC (Standardized AI-Powered Platform for Carbon-Negative Spider Silk Production)

To overcome the bottleneck, we established a Standardized AI-Powered Platform for Carbon-Negative Spider Silk Production, or SAC. SAC can be broken down into three major parts:


1. A Software Tool for Customized Spider Silk Sequence Generation

The Protein Folding Problem has long been attributed to the lack of understanding of a protein’s function; this same problem plagues spider silk protein production and application. However, through current advancements in Artificial Intelligence (AI) models such as Generative Pre-trained Transformer (GPT), our team was able to create a user-friendly software tool that can generate spider silk sequences with customized mechanical properties.


2. Sustainable Carbon-Negative Production of Spider Silk & Post-Processing

With a generated custom spider silk sequence, we can now synthesize and produce it with our specially designed production platform. Understanding the importance of sustainable manufacturing, our specially designed bioreactor uses industrial waste-water as a carbon-source to grow silk-producing BLR(DE3) E. coli.

To ensure that our production platform is truly carbon-negative, we created a model that considers the overall carbon-capturing ability of our platform as well as its economic benefits to companies interested in using or investing in our product.


3. Applications & Recycling