Contributions
Introduction
We have added new parts to the registry with information of its sequences and some details from the literature.
The information for each “parts registry” is in parts
These parts include inorganic and organic mercury sensors,
reporters and composite parts that improve the selectivity of organic mercury detection.
In line with this educational approach, we also developed a board game based on protocols commonly used by iGEM
teams for creating a bacterial biosensor. The game is designed to help newcomers to synthetic biology easily
understand the steps of this procedure. It can also be used at science fairs and outreach events to teach the
general public about the technical processes behind each project in an accessible and engaging way.
This year, as iGEM Bolivia, we focused on addressing mercury contamination caused by the recent rise of illegal
mining in Bolivia. To tackle this issue, we designed a biosensor for detecting this heavy metal in water. Our
contributions aim to raise awareness about mercury and its dangers through a dynamic educational tool called the
Mercury Game. We believe this interactive game will help others learn through play and can be valuable for many
future iGEM teams, especially as a tool for engaging children in scientific outreach.
Parts overview
| New iGEM parts | Type | Part's name | Description |
|---|---|---|---|
| BBa_K5257010 | Basic, Sensor | merRm4-1 | aTF repressor-activator sensitive to inorganic and organic mercury |
| BBa_K5257011 | Basic, Sensor | merRtn501 | aTF repressor-activator sensitive to inorganic mercury |
| BBa_K5257004 | Basic, Reporter | sfGFPmChartreuse | Optimized green fluorescent reporter |
| BBa_K5257000 | Basic, Reporter | mRFP_Magenta | Magenta fluorescent chromoprotein |
| BBa_K5257025 | Composite | NOT(TetR,TEV)-mRFP1magenta | Magenta reporter controlled by NOT logic gate. |
| BBa_K5257023 | Composite | LOT-MerA-GDH | Enzymes on the cell surface, a system for volatilization of Hg2+ without the need for NADPH. |
Mercury Game
Welcome to the Mercury Game!
Mercury, widely used in mining, is also a silent threat to the environment and human health. Through this game,
you’ll learn about the dangers of mercury, its impact on ecosystems, and how it accumulates in the food
chain.
How much do you know about this element? As you progress, you’ll discover important facts about mercury and its
influence on our surroundings. The goal is to leave you with a greater understanding of its effects and the need
for solutions like our mercury biosensor.
Start by answering the questions, and by the end, you’ll be more aware of the crucial role knowledge plays in
combating mercury contamination. Ready? Let’s get started!
Error
Board Mercury
This game teaches the step-by-step process of developing a mercury biosensor. The game includes cards that show
potential failures in the process, which could reduce the efficiency of a biosensor.
Primarily designed for entertainment and educational purposes, this game can be used at science fairs or as a
teaching tool for students interested in learning more about the development of biosensors.