The iGEM Bolivia team designed two new composite parts for the development of the organic mercury biosensor. All implemented parts have a theoretical foundation, however the iGEM Bolivia team is still in the experimental phase.

See all the new basic and composite parts

BBa_K5257025

New composite part for strategy 1

Magenta chromoprotein under the control of a NOT logic gate at the transcriptional level by TetR and at the post-translational level by TEV. This part is essential for the biosensor to be selective to organic mercury and to avoid activation in the presence of inorganic mercury. This new composite part can be used by other iGEM teams in the construction of biosensors.

Magenta reporter controlled by a NOT logic gate

BBa_K5257023

New composite part for strategy 2

MerA enzyme visualized on the cell surface without the addition of the cofactor NADPH. This part is essential for the biosensor to be selective to organic mercury by preventing inorganic mercury from entering the biosensor. This part represents our “Best New Composite Part” because the approach is totally novel, requiring only glucose and no cofactors such as NADPH. Our part BBa_K5257023 was implemented in a novel biosensor to improve the selectivity of organic mercury. It can be used by other iGEM teams to build a more effective bioremediation system against inorganic mercury.

BBa_K5257023 expresses the MerA enzyme that will localize to the cell surface.