Overview

Driven by the need to improve how cancer patients retain antibiotics in their system, our team developed a novel method involving a human albumin linking process to extend the half-life of these medications. Our project is guided by the principles of the engineering cycle. At a macro level, our approach follows an iterative design-build-test-learn process, transitioning from dry lab to wet lab. Additionally, our work is refined through micro iterations of the engineering cycle, focusing on the finer details to ensure optimal results.

Please click on the four components of the engineering design cycle graphics on the left to see all parts of our cycle iterations!

Protein Modeling

Albumin Binding Moiety Computational Design

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Wetlab (Micro)

Albumin-ABM Binding Design
Cycle 1: Protein Synthesis

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Cycle 2: Induced Binding

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Albumin-ABM-Linker Binding Design
Cycle 1

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Albumin-ABM-Linker-Cefepime Binding Design
Cycle 1

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Design
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ENGINEERING

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