Overview
Our product, the Vitamin B6 and B12 Anti-Motion Sickness Nasal Spray, came from our own experiences of feeling dizzy, nauseous, and even getting headaches after amusement park rides like roller coasters. These discomforts led us to think about motion sickness, a common issue that many people experience. This issue not only presents during thrill rides but also in their everyday lives. Whether they are traveling by car, plane, or boat. Motion sickness disrupts both travel experiences and daily commuting for a large number of individuals. We realizing that these people could benefit from a more convenient and effective solution, which we saw an opportunity to develop a product that would quickly relieve their symptoms without the need for traditional pills or other methods.
Research shown that people today increasingly prefer natural and healthier solutions, we began exploring the benefits of certain vitamins. Specifically, we focused on vitamins B6 and B12, which are known for reducing nausea and supporting the health of the nervous system. Our decision to create a nasal spray instead of other forms of medication was driven by its ability to provide faster absorption and ease of use. Especially for individuals who may need rapid relief from motion sickness while traveling.
Product Description
Our Vitamin B6 and B12 Anti-Motion Sickness Nasal Spray is designed to help relieve the uncomfortable symptoms of motion sickness, including nausea, dizziness, and headaches. Unlike traditional treatments, such as pills or patches, which can take longer to work or be inconvenient, our nasal spray provides rapid relief. It allows the active ingredients to enter the bloodstream directly through the nasal membranes, leading to a faster effect. The spray is small, portable, and easy to carry, making it an ideal companion for travelers on the go. Whether by car, airplane, boat, or train. It is particularly useful for those who experience motion sickness during long trips or daily commutes. The vitamins spray not only reduce symptoms but also provide an additional boost of energy and help users maintain mental clarity during their travels.
The mix of Vitamin B6, which is effective in reducing nausea, and Vitamin B12, which helps support neurological function, allows our nasal spray does more than just relieve motion sickness— it also supports overall well-being. This combination of ingredients ensures that users can travel more comfortably, free from the discomfort of motion sickness, while also receiving essential nutrients that benefit their health.
The principle of the product:
B vitamins such as thiamine (B1), pyridoxine (B6) and cyanocobalamin (B12) have antinociceptive effects in experimental animals with acute and chronic pain linked with neuronal injury. Vitamins B6 and B12 have been shown to counteract the deleterious effects of ischemia on neurons. These vitamins play important roles in nutrition, nerve conduction, axonal transport, synthesis of neurotransmitters and excitation via cyclic guanosine monophosphate (c-GMP) signaling pathway. Therefore, reconstructive activity of vitamin B complex on degenerative nerves may facilitate the recovery of nerve function after peripheral nerve injury. Resolution of peripheral nerve injury may benefit from a multinutrient treatment approach since vitamin B complex are necessary for optimum functioning of the nervous system. Unavailability of these vitamins may decrease the enzymatic activity of some enzymes and result in neurotoxicity.
(From a paper)
Related experiments
In a study, researchers conducted experiments using mice. According to their experiments, the nerves of mice showed significant improvement after taking B-class vitamins
(Altun, Idiris M.D. 1, *; Kuruta ş, Erg ü l Belge2 Vitamin B complex and vitamin B12 levels after peripheral nerve injury. Neural Regeneration Research 11(5):p 842-845, May 2016. | DOI: 10.4103/1673-5374.177150 ）
Market research and positioning
1. Target market determination: Clearly identify the main target audience for the product, such as roller coaster enthusiasts who experience strong discomfort reactions after riding a roller coaster, hikers, people with functional disabilities in the front desk, and those with a tendency to experience dizziness.
Competitor analysis
(1) Study the advantages and disadvantages of existing dizziness drugs and inhalation therapy products in the current market. The existing drugs on the market include halo patches, oral medications (pheniramine hydrochloride tablets, catecholamine tablets), halo creams, oral liquids, etc. Inhalation drugs are mainly respiratory drugs, such as asthma drugs (budesonide suspension, salbutamol sulfate), nasal ventilators, cough medicines, etc.
Dizzy Patch
Advantages: Convenient and easy to use: Halo patches are usually designed in the form of patches, which can be directly applied to acupoints such as the ear or navel, without the need for oral or injection, and are easy and fast to use. Long lasting effect: The drug ingredients penetrate and absorb through the skin, and can continue to exert their effects, generally lasting for several hours, providing a long-lasting dizziness relief effect for the patient. Wide applicability: Suitable for dizziness symptoms caused by various modes of transportation, including automobiles, motorcycles, airplanes, ships, etc., providing convenience for passengers of different modes of travel. Non drug dependence: Compared to oral medication, Halo Patch avoids potential side effects and dependence caused by drug metabolism in the body, making it safer and healthier.
Disadvantages：may cause allergic reactions: Some people may have allergic reactions to certain ingredients in the dizziness patch, such as redness, swelling, itching, etc. Skin testing should be conducted before use. The effect varies from person to person: The effect of the halo patch varies from person to person, and some people may have insignificant or completely ineffective effects. This may be related to factors such as individual constitution, degree of dizziness, and usage methods. Usage restrictions: Halo patches are generally not recommended for pregnant women, breastfeeding women, and children, as the drug ingredients may have adverse effects on fetuses, infants, or children. In addition, patients with severe heart disease, hypertension and other diseases should also use it under the guidance of a doctor. Possible impact on driving: Although dizziness patches can alleviate dizziness symptoms, some people may experience drowsiness, delayed reactions, and other symptoms after use, which may affect driving safety. Price factor: Compared to some traditional methods of dizziness relief such as oral medication, the price of dizziness patches may be relatively high.
Oral Halo Medications
Advantages:Effectiveness: Compared to other methods such as dizziness patches, it is more effective in preventing or relieving dizziness symptoms. Diversity: There are various dizziness drugs available on the market, such as Defenidor Hydrochloride Tablets, Phenobarbital Scopolamine Tablets, etc., to meet the needs of different populations.
DisadvantagesSide effects: Possible side effects include dry mouth, drowsiness, headache, etc. Overdose may also lead to acute poisoning or mental disorders. Dependence: Frequent use of stun drugs during menstruation may lead to a certain degree of dependence. Limitations: Pregnant women, breastfeeding women, children and other special populations should be used with caution.
Car sickness oral solution
Advantages:
Effectiveness: Oral ingredients for motion sickness, such as Gouteng and Chrysanthemum, have sedative, antihypertensive, and calming effects, which help alleviate the symptoms of motion sickness
Discomfort.
Safety:
As a traditional Chinese patent medicines and simple preparations, carsickness oral liquid is relatively safe, with relatively small side effects, but it should be forbidden for those who are allergic to ingredients.
Convenience:
Oral liquid formulations are easy to take without chewing or dissolving, suitable for various populations.
Disadvantages
Side effects: Some oral liquids for motion sickness may cause side effects such as dry mouth and drowsiness. Caution should be exercised based on individual physical condition and medication response
Use it.
Limitations:
Pregnant women, breastfeeding women, children and other special populations should be used with caution.
Inhalation drugs
Advantages:
Direct and rapid: Inhalation drugs can directly act on the respiratory mucosa, take effect quickly, and are particularly suitable for the treatment of respiratory diseases.
High local concentration: Due to the direct action of the drug on the lesion site, the local drug concentration is high, which can improve the therapeutic effect.
Small dosage: Compared to oral medications, inhaled medications require a smaller dosage, reducing the potential adverse reactions associated with systemic use.
Less systemic side effects: Drugs mainly act locally, reducing their circulation and metabolism in the body, resulting in relatively fewer systemic side effects
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Easy to use: Inhalation medication devices are compact and lightweight, convenient to carry and use, and suitable for patients to operate on their own.
Dependence:
Long term and frequent use of inhaled medications may lead to a certain degree of dependence.
Disadvantages
Difficult to control drug dosage: The dosage control of inhaled drugs is relatively difficult, and excessive use may lead to adverse reactions.
Possible irritation:
Some drugs may have a stimulating effect on the respiratory mucosa, causing discomfort.
2.Identify the differentiated competitive advantages of one's own product, such as vitamin composition, inhalation efficacy, portability, etc.
As an inhaled vitamin carsickness spray, its own product has opened up a new category of carsickness drugs on the market. Treatment with Vitamin B6 and B12 The effectiveness of vestibular dysfunction and dizziness makes it a core active ingredient, and the use of nanomaterials to wrap it reduces air loss and safety Effectively deliver drugs into the nasal cavity. The presentation of its spray uses inhaled drugs with small dosage, large local effects and side effects The advantages of being smaller make it superior to other motion sickness medications. Market demand forecast
Based on the growth of the tourism industry, increased population mobility, and rising consumer health awareness, predict potential market demand. Continuous growth in demand: With the growth of the tourism industry, increased population mobility, and rising consumer health awareness, there is a growing demand for motion sickness medication. The demand for quantity will continue to grow. Especially new drugs such as inhaled vitamin car sickness drugs will gradually become the new favorite of the market. Diversified demand: There are differences in the demand for motion sickness drugs among different consumer groups. For example, children may need safer and easier to use medication Object; Long distance travelers may place greater emphasis on the durability and convenience of medication. Therefore, the market will exhibit diverse demand characteristics. Brand competition intensifies: With the growth of market demand, more companies will invest in the research and production of inhaled vitamin car sickness drugs. this It will lead to intensified market competition, while also promoting the improvement of product quality and rationalization of prices. Innovation driven technology: The development of inhaled vitamin car sickness drugs will be driven by innovative technology. With the advancement of pharmaceutical technology and consumption With the continuous improvement of medication experience, innovative technologies such as new drug delivery methods and more efficient active ingredients will continue to emerge, injecting new energy into the market New vitality.
2、 Product development and innovation
1. Product formula and technical research and development
The common characteristic between those who experience significant discomfort while riding roller coasters and those who suffer from motion sickness is incomplete vestibular function. Therefore, we have chosen to have the option to be directly affected
The core active ingredients absorbed by the human body are vitamin B6 (pyridoxine) and vitamin B12 (cobalamin). Vitamin B6 ginseng
The synthesis of multiple neurotransmitters helps maintain the normal function of the nervous system. When the function of the front courtyard is impaired, vitamin B6 can assist
Promoting the repair process of the vestibular nerve can help alleviate symptoms. Vitamin B12 is a key nutrient for maintaining neurological health
1、 It is crucial for the normal growth and division of nerve cells, while also helping to maintain the integrity of the nerve sheath. In vestibular function
In abnormal situations, vitamin B12 can improve the symptoms of vestibular dysfunction by nourishing the nerves. On the material package, choose
Nanomaterials, because of their small particle size, make the atomized particles in the spray process more uniform and fine
The spray coating material has various functional characteristics, such as antibacterial, antifouling, anti-corrosion, etc. Due to the encapsulation technology of nanomaterials and inhalation atomization
The development of Zhidu is relatively mature, and we only need to focus on the core components when designing products.
2. Product design and packaging
Design portable and easy-to-use inhalers to ensure easy use in different scenarios.
The packaging should have sealing and moisture resistance, and meet environmental protection requirements.
Design different packaging for different user groups, such as small capacity designed for roller coaster enthusiasts, with bright packaging colors and cartoon shapes
Same color with different fruit aromas; The packaging designed for individuals with vestibular dysfunction is based on a gray white color scheme, which is concise and clear, highlighting the function
Ability and efficacy.
3、 Production and Supply Chain Management
1. Production planning
Based on market demand forecasting, develop production plans to ensure sufficient product supply. For example, increasing production during the peak tourist season to ensure sufficient supply of goods
Feet.
Introduce advanced production equipment and management systems to improve production efficiency and product quality.
2. Supply chain optimization
Establish stable raw material procurement channels to ensure the quality and supply stability of raw materials.
Strengthen cooperation with suppliers, reduce procurement costs, and improve overall supply chain efficiency.
4、 Customer Service and After sales Support
1. Customer Service
Provide professional pre-sales consultation and after-sales service, answer customer questions, and handle customer complaints.
Establish a customer database, regularly collect customer feedback, and continuously improve products and services.
2. After sales support
Provide product usage guidance, maintenance and other after-sales services to ensure that customers can use the product correctly. Establish a rapid response mechanism and ensure timely delivery
Handle product issues and improve customer satisfaction. Equipped with corresponding manuals, the online sales platform is equipped with customer service responsible for answering questions and resolving doubts
Pharmacist.
5、 Continuous research and innovation
1. Technical research and development
Continuously monitor the development trends of medical technology, continuously introduce new technologies and materials, and improve product performance. Continuously monitor for any new developments
Effective ingredients can replace vitamins and continue to innovate ingredient formulas.
Strengthen cooperation with research institutions and universities to promote product innovation and technological upgrading.
2. Product iteration
Based on market feedback and customer demand, continuously optimize product design and formula, launch new or upgraded product formulas, and adjust according to market conditions
Timely change marketing strategies to ensure no information lag or barriers.
SWOT
1.Strength
Our product is an inhaled medication, which has the following advantages compared to other medications
And our raw material is vitamins, which are basically harmless to people's bodies. Unlike other motion sickness drugs, which are composed of complex chemicals, long-term use may cause certain damage to people's digestive function., Some patients may even cause damage to the nervous system. Here is a case of motion sickness medication: Xiao Zou and his girlfriend Xiao Deng are preparing to rush back to their hometown in Guanghan from Chengdu. Before getting on the car, they each bought a pill for motion sickness. Xiao Zou bought an oral pill, while his girlfriend Xiao Deng chose an topical motion sickness pill that was placed behind her ear. A few minutes before getting on the car, Xiao Zou swallowed the car sickness medicine.
Less than 20 minutes after the car hit the road, his girlfriend Xiao Deng suddenly noticed several red blisters on Xiao Zou's hands, followed by his limbs turning red and his upper lip swelling. Got it, maybe she's allergic, "Xiao Deng was shocked. She knew that Xiao Zou was allergic to painkillers, and when she went to the pharmacy to buy motion sickness medicine, she even consulted a doctor about whether she could take it, and the answer she received was that it could be used.
Due to severe skin allergies, Xiao Zou was immediately taken to the hospital for treatment. That night, Xiao Zou developed a high fever with a body temperature of 39 ℃. Two days later, when the doctor examined him, he found that his whole body was red, swollen, and blistered, and a piece of skin on his hand had actually fallen off. The hospital recognized the severity of his condition and advised him to transfer immediately.
Allergic to medication, avoid medication symptoms
The car sickness medicine Xiao Zou took is a small pill called "Phenobarbital Scopolamine Tablets", which is a white pill about the size of a pea and sells for one yuan per pill. It's just such a small piece of motion sickness medicine, it's causing him so much pain, "Xiao Deng said, holding a small piece of motion sickness medicine.
The doctor explained that Xiao Zou's condition is a typical "medication syndrome", which refers to a disease caused by improper medication. He is taking barbiturates for motion sickness, which may cause severe drug sickness. There is no problem with the medication itself, but it is due to individual differences that this situation is caused. In other words, he is allergic to this medication and cannot use it
The doctor said that if the condition further develops, not only will the patient's skin peel off, but their liver and kidney function may also be affected, endangering their life. Doctors suggest that people with a history of drug allergies should be careful and cautious when taking medication to avoid accidentally taking medication and causing "drug symptoms".
2.Weakness
It is difficult to determine the competitiveness and market effectiveness of innovative products. New products may face fierce competition and threats from existing competitors, potential competitors, substitutes, etc. If the product cost is too high, the design has defects, and the quality is unstable, it will affect its competitiveness. In addition, if the product is found to have side effects or cause environmental pollution, ecological damage, etc. after being launched, it may be subject to legal restrictions, directly affecting the success of innovation
3.Opportunities
Conduct necessary clinical trials to verify the safety and effectiveness of the product.
Apply for relevant medical certifications to ensure that the product is legally marketed.
3、 Marketing Strategy and Brand Building
1. Brand positioning
Emphasize the characteristics of the product's vitamin content, safety and effectiveness, portability and ease of use, and establish the brand image.
The brand positioning is for popularization, with a market position that meets the needs of ordinary consumers, emphasizing the brand's approachability and popularity
Sex and wide applicability, aimed at attracting and covering a wider range of consumer groups.
The image of the marketing brand mascot Squirrel Girl "Songzi" has become widely known and deeply ingrained in people's hearts.
2. Market promotion
Promote the image and brand products of "Matsuko" on social media, and advertise through channels such as social media, travel websites, airlines, etc
Release and collaborate on promotion. Sell related merchandise of 'pine nuts' online to increase visibility.
Organize product launches, experience events, participate in public welfare activities, and increase brand exposure. Collaborate with well-known IPs to enhance brand awareness
Degree. For example, by linking with the Keep platform, it can be sold directly on the Keep official website; Linkage with Genshin Impact can promote Genshin Impact players to buy and
Improve the popularity among anime people.
3. Sales channel construction
Collaborate with pharmacies, airports, tourist attractions, amusement parks, etc. to establish sales networks. You can try to communicate with Disney, Universal Studios and other visitors
Large well-known theme parks are linked and sold within the park,
Simultaneously opening an online mall to provide convenient purchasing channels.
4.Threaten
Marketization of technical risks. New products may be rejected by consumers or attacked by competing products during the marketing process due to the immaturity of the technology itself. In addition, commercialization risk is also a major challenge. If marketing power cannot promote the formation of market purchasing power, brand power cannot promote the formation of sales volume, and the launch of new products may not help enterprises increase economic benefits Legal risks. The development of new products requires compliance with relevant laws and regulations. If enterprises do not fully understand and comply with relevant laws and regulations, they will face legal risks, which will affect the promotion and sales of new products Marketing strategy flaws. New products may have low market acceptance due to a lack of clear marketing strategies. For example, if there are no "stunning" elements or attractive value propositions in the product, it may not be able to stimulate customers' interest. Improper management. The development of new products requires professional project management and team collaboration. Improper management by the enterprise can affect the progress and quality of new product development, resulting in products being unable to be launched on time or having poor quality
Product innovation
Extending from motion sickness:
Seasickness, airplane sickness, blood sickness, and altitude sickness. These common dizziness symptoms can be alleviated through motion sickness medication, as the principle of motion sickness medication is that antihistamines in motion sickness medication bring drowsiness to patients, thereby eliminating drowsiness.
It should be noted that dizziness caused by cerebral ischemia (darkening the eyes) after waking up at night may not be relieved with motion sickness medication. In addition, some vertigo caused by brainstem lesions, cortical lesions, and vestibular lesions cannot be relieved by motion sickness medication.
insomnia
The principle of motion sickness medication is as follows: 1. It has an inhibitory effect on the chemoreceptors that induce vomiting in the brain, mainly exerting a central inhibitory effect on vomiting, reducing the nausea and vomiting sensation that patients may experience during motion sickness.
2. Inhibiting the sensitivity of the vestibular organs to acceleration stimuli, some patients may suddenly accelerate or decelerate while driving, and after taking motion sickness medication, they may become very insensitive. This is because motion sickness medication can reduce the nerve impulses caused by movement and alleviate uncomfortable symptoms such as dizziness.
3. The main principle of action of car sickness drugs is that they are antihistamines. After taking them for half an hour, patients will experience a state of drowsiness, inhibit glandular secretion, feel particularly sleepy and drowsy, and have dry mouth and tongue, which can suppress the occurrence of dizziness, nausea, and vomiting in patients.
Based on these two points, if insomnia patients take motion sickness medication, their nerve impulses and central receptors will be suppressed, and drowsiness will significantly increase.
Related to vestibular function - hearing allergies (sound allergies), "excessive gyroscope parameters in the human body", and "oral epilepsy"
You can use motion sickness medication because hearing allergies, flexibility in movement, and oral movements are all related to vestibular perception. Car sickness medication aims to reduce the sensitivity of vestibular sensation.
Vestibular dysfunction is characterized by poor balance, easy falling while walking, poor distance control, clumsy movements, and vestibular dysfunction. People with vestibular dysfunction often cannot judge visual space and cannot grasp distance and direction well; It is easy to encounter problems such as skipping words, missing words, serial connections, and inversion when reading. In addition, due to the processing disorder of the vestibular center, it cannot effectively filter various information such as vision and hearing. The human brain receives a large amount of information, which puts a heavy burden on the brain and can easily manifest as problems such as lack of concentration and distraction. The above problems can be solved with motion sickness medication.
Future Development and Planning
There are several other methods to alleviate dizziness besides vitamin spray which we would like to study further. First, medications such as antihistamines (Dramamine, Bonine) and scopolamine patches work by blocking the signals in the brain that trigger nausea and dizziness, making them highly effective for motion sickness. Second, acupressure bands apply pressure to the P6 point on the wrist, which helps to interrupt the nausea and dizziness signals sent to the brain, providing significant relief. Third, vestibular rehabilitation therapy offers specialized exercises that improve balance and train the brain to adapt to imbalanced signals from the inner ear, addressing the root cause of dizziness.
Production of soothing nasal suction complex
Based on the success of our experiments and research, we attempted to develop a product related to our study. Through thoughtful product design, the development process has shown promising results. Below is our production process.
Ursolic acid nanoparticles were prepared by ultrasonic emulsification method, and the morphology was observed by SEM. Ursolic acid was successfully prepared into nanoparticles. Agilent 1290 liquid chromatography was used to detect encapsulated vitamins, with the following liquid phase
Mobile phase: 0.2% formic acid water (A) - acetonitrile (B), flow rate of 0.2 mL/min
Gradient elution conditions: 0-0.5min, 30% B; 0.5-2min，30-80% B; 2-3min，80-98% B； 3-5min，98% B; 5-7min，98-30% B; 7-9min，30% B; 9 minutes, stop.
Injection volume: 2 μL, column temperature: 35 ℃, detection wavelength: 330nm.
Production of soothing nasal suction complex: the concentration of Vb6 was 25 μM, the concentration of Vb12 was 2.5 μM (Vb6:Vb12=10:1), the concentration of PLP1 protein was 5 μM, the solution was normal saline. All the procedures were performed under aseptic environment.
