During this year's iGEM project, we received support from various sources, and without them, our current achievements would not have been possible. We would like to express our sincere gratitude.

We thank Nanjing Tech University, the School of Biological and Pharmaceutical Engineering, the Laboratory Management Office, the Experimental Center, and the Logistics Support Office for their assistance.

We are grateful to Professor Gong Changbin from the School of Biological and Pharmaceutical Engineering for his support and help with the experiments.

Our thanks also go to Zhang Yabing, the laboratory safety management leader, for his management, supervision, and assistance in the laboratory. We appreciate the IBD patients who helped us understand their treatment journeys and the current social context.

We thank Bota Cui for providing advice on bacterial therapies, which inspired the design of our project.

We are grateful to Shuai You for offering professional advice on protein expression.

We thank Wuhan University, Hubei University, Lanzhou University, Tsinghua University, Peking University, and Nanjing University for collaborating with us on topic and project exchanges and for co-authoring the EcN white paper.

We appreciate Jiangsu Provincial People's Hospital for providing us with professional knowledge related to IBD.

We are thankful to the Regulatory Authorities for helping us understand the regulatory policies regarding synthetic biology bacterial drugs and for providing recommendations to ensure safety.

Lastly, we thank Jiangsu Suzhong Pharmaceutical Research Institute for their assistance with drug delivery.