James Sturgis is a distinguished professor and researcher at Aix-Marseille University (amU). He works at the CNRS, in the Laboratoire d'Ingénierie des Systèmes Macromoléculaires (LISM, UMR7255), where he leads the research team titled "Dynamics and Assembly of Membrane Proteins". His group focuses on understanding the folding and assembly mechanisms of membrane proteins. Specifically, their research explores how these proteins organize in the membrane to form either stable structures, such as the photosynthetic apparatus, or transient, dynamic complexes.
"I'm Associate Professor at Aix-Marseille University and I work at the CNRS, in the Laboratoire d'Ingenierie des Systèmes Macromoléculaires (LISM, UMR7255). Our team aims to understand the assembly and function of conserved macrocomplexes present in the envelope of Gram-negative bacteria: the Tol and Ton systems. These protein assemblies, involved in cell adaptation and survival, are also the gateway for bacterial toxins and viruses. More specifically, I'm trying to understand how a specific class of viruses called filamentous phages can cross the host envelope. My fundamental projects aim to open up longer-term perspectives in the development of phages for therapeutic purposes."
- L. HOUOT
Ize Bérangère is a research scientist and the group leader of the Pseudomonas aeruginosa Pathogenicity team within the Laboratoire d'Ingénierie des Systèmes Macromoléculaires (LISM, UMR7255). Her research team is dedicated to investigating the molecular mechanisms that drive the virulence of the model organism Pseudomonas aeruginosa, aiming to deepen the understanding of its pathogenicity.
Jonas Desjardins is a PhD student and a member of E. Cascales’s team, titled "Assembly of Bacterial Multi-Protein Complexes," within the Laboratoire d'Ingénierie des Systèmes Macromoléculaires (LISM, UMR7255). The team’s primary goal is to uncover the molecular mechanisms that govern the assembly, structure, and function of multiprotein complexes associated with the cell envelope in Gram-negative bacteria, with a particular focus on secretion systems. Jonas was also a former participant in the 2019 iGEM competition with the Aix-Marseille University team ('I WANT TB FREE'), where he contributed his personal expertise to the project.
Valérie Prima is an assistant engineer working within the Laboratoire d'Ingénierie des Systèmes Macromoléculaires (LISM, UMR7255). She is part of the Dynamics and Assembly of Membrane Proteins research group. The group focuses on the folding and assembly of membrane proteins, investigating how these proteins organize within the membrane to form stable structures, such as the photosynthetic apparatus, or more transient, dynamic formations.