PUBLIC ENGAGEMENT FOR EDUCATION AND DISSEMINATION OF ENTHUSIASM FOR OUR PROJECT AND SYNTHETIC BIOLOGY IN GENERAL.
Materials
We have produced different promotional materials to promote our project in many ways.
Audience
The main groups we educate are students with different cognitive levels, the general public, the elderly, pregnant women and children with disabilities.
Approach
We developed different strategies based on different groups' understanding of synthetic biology, and used different communication tools based on the practical importance of our project.
Education Tools
We believe that using a variety of educational tools can expand the educational community, and we have created DHA cookbooks, synthetic biology fairy tales, synthetic biology comics, biological brick diagrams, and enzyme optimization tools to help the public understand synthetic biology and delve into the construction process of synthetic biology. We publish all our original synthetic biology tools on online platforms, including XiaoHongshu, wechat public account, instagram, zhihu, etc. In addition, our educational tools are also used in all the educational activities listed below to contribute to the continuous dissemination of synthetic biology.
Bio Tales
XJTLU
CHINA
Synthetic biology fairy tales !
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Biological Fairy Tale
This year, XJTLU-CHINA created a fairy tale, Aggie’s Little Flower, to explain the concept of synthetic biology. Through the creation of characters and plots, such as a clever and brave adventurer and the stories of ‘Stinky Bacteria’ and ‘Ugly Bcateria’, children were able to follow the adventures of the protagonists and understand the principles of DNA editing and recombination in a vivid and graphic way. We also tell a ‘paper cut’ story, where children can understand how to combine the best features of organisms through scientific means to create new and better biological functions. We believe that a fun and entertaining format helps children remember what they have learnt for longer and maintains their interest in science. We post our fairy tales on social media to expand their distribution channels, and we print the stories as trifolds and distribute them at every educational event.
DHA recipe !
DHA Recipe
XJTLU
CHINA
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Recipe Details
Through our human practice activities and discussions with pregnant mothers, we learned that they were hoping to compile a DHA formula suitable for babies to support the development of the baby's nervous system and retina. To this end, we combined the suggestions of nutritionists and designed a supplement formula for babies aged 1-5 years and published it on the internet. By cleverly incorporating DHA-rich ingredients into your baby's diet, you can help your baby get important nutrients.
Biobrick Diagrams
XJTLU
CHINA
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Biobrick Details
To help the public understand the basic principles of synthetic biology, we have produced a biobrick diagram to help reduce misconceptions about genetic engineering among the public and to help the public understand how synthetic biology can design and modify biological systems through standardized and modular approaches. This will contribute to the scientific literacy of the public and help them to understand and accept modern biotechnology and its applications.
Biobrick Diagrams !
Software Tools !
Software Tool
XJTLU
CHINA
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Software Details
We have successfully optimized the UniKP enzyme model and developed a simple front-end interface. This user-friendly platform allows users to input their enzyme sequences and instantly receive the optimized enzyme sequences based on the model's output. The significance of this development lies in its ability to streamline the process of enzyme sequence optimization, making it more accessible for researchers and scientists. By simplifying the workflow, we are enabling faster and more efficient enzyme design, potentially accelerating advancements in biotechnology and other related fields. In our work of modeling and optimizing enzyme activity this year, we found that traditional methods were more complicated, we read articles extensively, we found Dr. Luo Xiaozhou's unikp model, we optimized the unikp model, and finally, users only need to input the sequence to obtain the optimized sequence, providing new ideas for traditional modelers
Synthetic biology comics
XJTLU
CHINA
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Synthetic Comic Details
This year, XJTLU-CHINA collaborated with JLU-NBBMS, CAU-CHINA, SUSTech-Med, JLU-CP, HainanU-CHINA, DKU-iGEM and Peking HSC to publish eight issues of synthetic biology comics by eight teams. Each team starts from a different application scenario of synthetic biology to communicate complex scientific concepts to a wider audience in a simple, intuitive, and fun way.
Promotion Manual
XJTLU
CHINA
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Promotion Manual Details
XJTLU-CHINA produced a brochure for the iGEM project, which was widely disseminated in the university, and we presented the team's research results and innovations to the public, academics, and potential partners. Through the brochure, we can effectively communicate the project's core concepts, technological breakthroughs and application prospects to attract more attention and support. At the same time, the production of the brochure also helped the team to hone its scientific communication and promotion skills, enhance its image, and lay the foundation for future collaborations, resource acquisition, and project continuation. Ultimately, this not only promotes the development of the project itself, but also promotes the popularisation and communication in the field of synthetic biology.
Education for Young Students
For younger students, we want to help them understand what synthetic biology is in more fun and interactive activities. We have designed some hands-on experiments, gamification learning, and stories and cartoons to stimulate children's curiosity and learning interest in synthetic biology. In our lectures, we explain complex scientific concepts in simple terms, such as comparing cells to cities and organelles to facilities in cities to help them understand basic cellular concepts. We also compare synthetic biology to the Lego of life and teach children that synthetic biology is a form of building blocks to create new functions.
Craft Activities
XJTLU
CHINA
DIY Craft activity - Make your own cell membrane !
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DIY Craft activity - Make your own cell membrane
At the end of the activity, the children asked a lot of questions, such as: “Why is the cell membrane made of two layers”, “What is the cell membrane made of?”, “Is there any difference between a real cell membrane and one made of playdough?”, “Are all the Do all things have cell membranes?”, we let them understand the concept of cell membranes through some figurative answers, such as cell membranes that would control entry and exit like the door of a house, and cell membranes that have a head that likes water and a tail that doesn't like water. We were happy to see the children actively asking us questions as they tried to understand complex scientific concepts, and we hope that through such interactions, we can motivate them to be more curious about the microcosm of biology and keep their spirit of exploration in science
Volunteer teaching in poor primary schools
Volunteer Teaching
XJTLU
CHINA
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Volunteer teaching in poor primary schools
We are concerned that there are several primary schools for the children of migrant workers in Suzhou, which tend to be more backward in terms of facilities and quality of education. So, we are planning to go to one of these schools - Suzhou Zangnan School for Volunteer Teaching
In the lecture, our team members introduced the types of microorganisms from our daily life, such as bacteria, fungi, and algae. We emphasize that microbes are everywhere: in the air, in the soil, on our skin and even in our stomachs. Hearing us describe it in this way, the students became frightened. We continued to explain to them that there are good and bad microorganisms, beneficial microorganisms such as probiotics, which help us to digest our food, but we also need to be aware of the harmful microorganisms in our lives, such as germs, which can make people sick and can be passed on to other people through coughing, sneezing, and touching food with dirty hands. Then, we took them through the concept of vaccines by explaining how to protect themselves from harmful microorganisms, and finally, we introduced some examples of synthetic biology by explaining that microorganisms in the soil can help plants grow and are an integral part of agriculture
After the talk, students gathered around, and we prepared succulents for them. We told them that succulents are easy to survive and tenacious, symbolizing the resilience and health of life, and in this way, we wanted to help them understand the cycle of life in nature. In addition, we also distributed three fairy tale pages that we had written, and the children said that they were very interesting and could understand the meaning of synthetic biology
Charity Education
XJTLU
CHINA
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Charity Education
As we organize events to enable more people to shape, contribute to or participate in synthetic biology, we find that disabled children are always overlooked. Disabled children are accompanied by congenital diseases and have more limited physical, perceptual and cognitive abilities. For this reason, our team of students wanted to help disabled children to the best of our ability, we contacted the Changzhou Welfare Institution, who eventually agreed to allow us to engage with the children in the institution, since a lot of them suffer from polydactyly as well as mental deficiencies, and even ADHD. We finally chose to convey the concept of genes to them by drawing pictures. We use different colors to represent different genes and show how they fit together, we give examples of how genes affect appearance, e.g. ‘You have black hair because your genes dictate this
Charity Education !
Biosafety Exhibition !
Biosafety Exhibition
XJTLU
CHINA
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Biosafety Exhibition
This event attracted about 30 students and parents to attend. The exhibition was divided into two parts, the first part was the bio-invasion prevention and control exhibition, which mainly demonstrated the work of the Customs, and the second part was the biodiversity exhibition, which mainly demonstrated biodiversity.
In the first part, we first explained the history of quarantine to bring students and parents to understand what is the national biosecurity, we also gave students and parents a physical display of important foreign organisms intercepted over the years, microorganisms that cannot be seen with the naked eye, we through the high-definition display system, clearly on the screen to see the specimens of the subtle morphological characteristics, in order to let children experience the work of the Customs staff. We arranged the container quarantine which is the key concern in quarantine work on the spot, and helped the experiencers to experience the daily work of the customs inspectors by observing whether there are weed seeds, ant paths in the containers themselves, and whether there are holes in the wooden packages for the aspens to bore holes, and we also designed a simulation area of the work of the postal inspectors, to help the experiencers to understand what is allowed to enter the country and what is not, and in the second part we arranged the Seed Wall, Butterfly Wall and Insect Wall to demonstrate biodiversity.
Approaching Alzheimer
XJTLU
CHINA
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Guardians of Memory: Approaching Alzheimer's Disease
On September 21, the day of Alzheimer's Disease, we were invited by the Affiliated High School of Xi 'an Jiaotong-Liverpool University to give an education on Alzheimer's disease to children in grade 7. In this educational activity, we first introduced the basic information of Alzheimer's disease, including its symptoms, as well as its impact on memory and functional cognition. Then we shared how to boost your brain and health by consuming foods rich in Omega-3 fatty acid. In this section, we detailed what DHA is. We emphasized that although DHA is not a direct cure for Alzheimer's disease, it can help reduce the risk of cognitive decline. We presented the project completed by the XJTLU-CHINA team this year - biological production of higher-absorbability DHA.
Guardians of Memory: Approaching Alzheimer's Disease !
Education for College Students
The prevalence of synthetic biology in universities is an important part of education that we take very seriously. To get more accurate and general feedback, we planned to use a questionnaire to investigate the popularity of synthetic biology. After a day's work, we found that the dissemination of synthetic biology is insufficient and most undergraduate students have not heard of synthetic biology and iGEM. Based on the results of the questionnaire and offline research, we summarize the following phenomena:
Students often see research as something far removed from themselves.
Many students lack confidence and feel intimidated when they see the word ‘competition’.
Some students studying art or business may see it as a scientific competition, such as. biology, and will not research it further.
Many EE students are not interested in biology competitions.
Biology and chemistry students are aware of synthetic biology and the iGEM competition, but they are more interested in the industry of synthetic biology.
Many teachers and students find what we are doing very interesting and agree with it.
We have summarized and categorized the above phenomena. The following sections provide detailed information about the problems and solutions:
Problem:
Lack of confidence
No experience in interdisciplinary competitions
Unfamiliarity with the details of synthetic biology
Poor information about developments in the synthetic biology industry
Solution:
Conduct Happy Hour events, organize professors and experts in the field to give personal development plans and advice to students who want to join the field of synthetic biology in the future.
Speak at conferences and encourage students to try out for the iGEM competition.
A summer programmed to explore synthetic biology, giving students the opportunity to learn about synthetic biology and the rules of the iGEM competition.
Create a community of students from different majors to discuss and exchange ideas on synthetic biology and iGEM to promote interdisciplinary communication.
Plan to use SynBio as a platform for students to explore synthetic biology and iGEM.
Plan activities with SynBio as the theme, connecting biology and engineering, explaining the concepts of biobricks and genetic circuits, and encouraging more students majoring in electronic information science to participate.
Happy Hour
XJTLU
CHINA
Happy Hour !
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Happy Hour Detail
According to the questionnaire, we are concerned that college students are vague about their career plans and have little information about the development of the synthetic biology industry. So, with the help of College of Pharmacy, Xi 'an Jiaotong-Liverpool University, we created an opportunity for students to have face-to-face communication with industry pioneers. We invited six experts, Dr Huang Baohua, Chairman and CEO of Tongyi Pharmaceutical; Dr Zhao Xiaojian, Founder, Chairman and CEO of Biinol; Dr Scott Matthew Wheelwright, COO of Biinol; Dr Sun Hong, Deputy Director of the Department of Endocrinology at the Fourth Affiliated Hospital of Soochow University; and Dr Ruan Gang, Professor of Huihu College of Pharmacy, Xi 'an Jiaotong-Liverpool University.
The experts shared their personal journeys from student to elite and the future trend of collaboration in the biomedical industry chain. The students had heated discussions with the guests on the correlation between scientific research and commercialization, and the links between synthetic biology and other disciplines.
Summer Programme
Summer Programme
XJTLU
CHINA
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Summer Programme
On the 28th of June, we published the recruitment information for the Summer Experience Camp, hoping to give freshmen who have just entered university the opportunity to learn and understand synthetic biology. After our launch, many students showed interest in the activity, so we successfully held the Summer Experience Camp.
In our summer experience camp, on the first day, we invited a PhD student of Biological Science from Xi 'an Jiaotong-Liverpool University and the coach of the XJTLU-CHINA team to explain the principles of synthetic biology. We also invited the XJTLU-CHINA 2022 team leader to teach the students how to build a complete iGEM project.
On the second day, we partnered with Duke Kunshan University and invited them to present a practical case study of the bioremediation track to our students. In addition, our team members actively presented our project, and we actively discussed our project with the participating students. They questioned our method of measuring enzyme activity. Inspired by them, we actively read the literature and chose a more efficient method of measuring enzyme activity - the enzyme coupling reaction method.
After the second day, we collected the opinions of the students who expressed their interest in iGEM SPACE-related track content, so we contacted the Space Track team extensively and finally found the Dulwich High School team in Suzhou with us. Dulwich High School is focusing on the Space Track this year, and we hope to cooperate with them, which provide a channel for the summer camp students to understand the Space Track.
On the third day, we went to Dulwich High School together to learn the Space Track with the Dulwich High School team, we learned that the Space Track needs to solve the challenges of future human exploration in space, and we also tried to negotiate a new space treaty with the Dulwich High School team.
At the end of the summer camp, the students all expressed their deep understanding of the iGEM competition and synthetic biology, and their desire to participate in next year's iGEM competition. Some students even created a ppt to share their achievements.
Work Shop
XJTLU
CHINA
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Workshop—Project Showcases
At the beginning of the semester, we ask the faculty for permission to introduce students from different academic backgrounds to the fascinating world of synthetic biology and the exciting iGEM competition. Our focus is to encourage 'cross-disciplinarity', and we make it clear that we strongly encourage students from all backgrounds, including business, humanities, engineering, and other subjects less directly related to biology, to take part in the competition. We set up our own synthetic biology booth on our campus, made beautiful posters, brochures and iGEM stickers to explain our project to students. What is more exciting is that we invited other students who had never entered the laboratory to carry out simple milk solid enzyme test, DNA extraction experiment and capsule experiment.
The response from the students was very positive, with many approaching our team after the presentation to express their keen interest in the competition and to ask for the brochure we had prepared.
In this event, we formed a community of about 60 people, and students said that they would like to continue to study synthetic biology, but they want to do it in a more academic way, and they look forward to learning synthetic biology in the classroom.
Workshop—Project Showcases !
SynBio !
SynBio
XJTLU
CHINA
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SynBio Details
After we presented our project on campus, we created a synthetic biology community, students from different majors expressed their desire for a more in-depth event to help them learn what synthetic biology is, therefore, we held a synthetic biology event with SynBio as the theme, firstly, we showed the students the BioBricks Guidebook that we made to help them understand the concept of synthetic biology parts, based on this, we explained to the students what gene lines are and how to construct them, secondly, in order to demonstrate more intuitively how to search for parts in an igem project, we contacted the NJU-CHINA , and with their permission we were able to use their AI software to search for parts quickly, the students were very interested in the students showed great interest in the integration of synthetic biology and ai and gave us feedback on their experience. Finally, we held a discussion on whether we should use synthetic biology to produce dietary supplements. The students from social sciences and business actively expressed their opinions on cost, ethics, and safety, and emphasized the need to ensure the safety of our products and to meet the stringent regulatory requirements, and the need to ensure the safety of the products. They emphasized that we need to ensure that our products are safe and meet stringent regulatory requirements, and that we need to go through a series of safety standards and certification procedures by international regulatory bodies such as the FDA and EFSA to ensure that synthetic biology products undergo stringent safety tests before they are introduced to the market, while Biology students expressed their concerns about our project in terms of the technical difficulties involved, which they believed lay in the purification of high purity and active proteins in different buffer environments. Through this seminar, both sides explored the unification issues under different perspectives and ways of thinking, promoted the mutual learning of knowledge and views, and inspired the XJTLU-CHINA team to think about this project in a brand-new way.
CCiC
XJTLU
CHINA
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CCiC Details
From July 11 to July 14, we hosted the 11th Conference of China iGEMer Community (CCiC), which aims to provide a resource sharing platform for the participating iGEM teams and young Chinese synthetic biology enthusiasts to promote mutual learning and exchange. At the CCiC conference, iGEM teams from all over China gathered to exchange project design and progress. We designed an event like Jamboree, where each team gave a speech, the judge asked questions and suggestions for each team, and there were also experts and scholars in the field of synthetic biology address excellent lectures.
We invited 123 iGEM teams and more than 600 to participate in this activity. For participants to get to know their projects more quickly, we collected the information of all the teams and made a participation manual for everyone's reference. We also designed a poster display area for each team to communicate and discuss their projects.
In the CCiC, various university teams actively exchanged and presented their projects, and we received feedback from many teams, who expressed their gratitude for having such an opportunity to communicate.