Do you know how much plastic
is produced each year?
Plastic Waste
Approximately 359 million tons.
The world is faced with an increasingly
serious problem of plastic pollution.
PET
Among them, PET accounts for 80 million tons.
There are various methods of
plastic
degradation......
photodegradation
It is highly influenced by environmental factors.
thermal degradation
The recycling cost is high.
enzymatic degradation
Enzymatic degradation is popular because of environmentally friendly.
But!
enzymatic degradation
Enzymatic degradation is not efficient
enough.
So we screened target PET-binding peptides
based on LSTM and GCN models.
Our model
initially learns the features of non-target peptides through supervised learning with labeled
data.
That's not quite right.
Our model learns the features of target peptides from positive data.
Good job,my little one!
Our model screens potential target peptides when faced with new, unlabeled data.
Our model successfully screened out the target peptides!
Finally, we successfully boosted
the degradation efficiency of
PETase
towards PET microplastics through
the fusion of
PET-binding peptides.
PETase
linker
PET-binding peptide
PETase
linker
PET-binding peptide