Parts
Introduction to COALES Parts
As part of our iGEM project, we have designed and characterized a set of biological parts that contribute to the core functions of our drug delivery system. Each part is a carefully engineered segment of DNA that performs specific roles, such as specific binding with the cancer cell, escaping endosomal degradation, or release of drug at a certain pH range. These parts are designed to be modular, following the BioBrick standard, allowing them to be easily assembled and integrated into different biological systems.
Our collection includes foundational elements like protein domains and linkers as well as more complex composite parts that combine multiple functions. We aim to ensure that each part is not only functional but also thoroughly characterized, providing valuable tools for future iGEM teams and researchers in the synthetic biology community.
New Basic Parts | |||
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Name | Part Number | Type | Link |
p160 Tumor Homing peptide | BBa_K5137000 | Protein domain | https://parts.igem.org/Part:BBa_K5137000 |
PMAP | BBa_K5137005 | Protein domain | https://parts.igem.org/Part:BBa_K5137005 |
Endosomal protease cleavage site | BBa_K5137007 | Protein domain | https://parts.igem.org/Part:BBa_K5137007 |
SMT3 | BBa_K5137001 | Protein domain | https://parts.igem.org/Part:BBa_K5137001 |
mfp1 | BBa_K5137002 | Protein domain | https://parts.igem.org/Part:BBa_K5137002 |
Linker for TV1 | BBa_K5137003 | Protein domain | https://parts.igem.org/Part:BBa_K5137003 |
SpyTag 002 | BBa_K5137004 | Protein domain | https://parts.igem.org/Part:BBa_K5137004 |
SpyCatcher002 | BBa_K5137006 | Protein domain | https://parts.igem.org/Part:BBa_K5137006 |
ADF3 | BBa_K5137008 | Protein domain | https://parts.igem.org/Part:BBa_K5137008 |
Linker for CfaN | BBa_K5137010 | Protein domain | https://parts.igem.org/Part:BBa_K5137010 |
CfaN | BBa_K5137011 | Protein domain | https://parts.igem.org/Part:BBa_K5137011 |
CfaC | BBa_K5137013 | Protein domain | https://parts.igem.org/Part:BBa_K5137013 |
CGG-repeat | BBa_K5137015 | Protein domain | https://parts.igem.org/Part:BBa_K5137015 |
Reused Basic Parts | |||
---|---|---|---|
Name | Part Number | Type | Link |
Hexahistidine-tag | BBa_K1362468 | Tag | https://parts.igem.org/Part:BBa_K1362468 |
New Composite Parts | |||
---|---|---|---|
Name | Part Number | Type | Link |
Target component (alternatively named as pYY8aTV1) | BBa_K5137500 | Composite | https://parts.igem.org/Part:BBa_K5137500 |
Drug Component (alternatively names as pYY3c-L-CfaN) | BBa_K5137501 | Composite | https://parts.igem.org/Part:BBa_K5137501 |
Drug payload (alternatively named as pCfaC-CGG8) | BBa_K5137502 | Composite | https://parts.igem.org/Part:BBa_K5137502 |