Project Description

Describe how and why you chose your iGEM project.

Bronze Medal Criterion #3

Describe how and why you chose your iGEM project.


Please see the 2024 Medals Page for more information.

Construction and optimized regulation of system for efficient degradation of corn straw to produce volatile fatty acids with rumen microorganisms.


Lignocellulosic biomass is the most abundant renewable resource, and its anaerobic fermentation for the production of volatile fatty acids (VFAs) is a very cost-effective method of biomass resourcing, and VFAs and their derivatives have a wide range of potential applications. The special organizational structure of lignocellulose makes its hydrolysis a rate-limiting step in anaerobic fermentation, leading to inefficient conversion of lignocellulose, high production costs, and difficulties in large-scale commercial production. The rumen digestive system of ruminants has the ability to degrade lignocellulose efficiently, in which rumen microorganisms play an important role. Therefore, rumen microorganisms are promising for efficient degradation of lignocellulosic biomass for the production of VFAs.This project proposes to artificially construct an efficient rumen microbial anaerobic fermentation system for the production of VFAs from biomass waste and optimize the regulation. The specific contents include (1) analyzing the composition of efficient hydrolytic and acid-producing bacterial and fungal communities in rumen microecology; (2) constructing the system of mimicking the efficient anaerobic fermentation of rumen to produce VFAs; (3) optimizing and regulating the system of mimicking the efficient anaerobic fermentation of rumen to produce VFAs; and (4) revealing the mechanism of action of mimicking the system of mimicking the efficient anaerobic fermentation of rumen to produce VFAs. The construction and optimization of acid production system for biomass. The research results are of great significance to the biomass resource utilization, which can increase the industrial scale of biomass resource utilization and provide technical guarantee to support the construction of ecological civilization.

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References


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