In 2019, there were 178 million new fractures reported worldwide. Bone defects, including those resulting from spinal fusion surgeries, fracture repairs, and congenital abnormalities, are a growing challenge in China.
The rising demand for effective treatments highlights the need for advanced bone regeneration techniques, as conventional methods often fall short in fully restoring complex or large-scale defects.
We aimed to develop an innovative approach to bone defect using synthetic biology.
Through an integrated cycle of development, our ultimate goal is to provide a dual-factor releasing collagen hydrogel for bone repair, incorporating VEGF and BMP-4 to sequentially promote angiogenesis and osteogenesis, thereby addressing complex bone defects.
The technologies we have developed are highly effective and rigorously standardized, ensuring robust performance and reliability in achieving controlled, dual-factor release for enhanced bone repair.
Just as fertilizer fuels plant growth, our dual-factor releasing collagen hydrogel delivers essential factors—VEGF and BMP-4—to accelerate and enhance the natural bone healing process, revolutionizing the future of bone repair.
